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Intestinal expression of P-glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate-glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetimibe in humans.
Oswald S, Haenisch S, Fricke C, Sudhop T, Remmler C, Giessmann T, Jedlitschky G, Adam U, Dazert E, Warzok R, Wacke W, Cascorbi I, Kroemer HK, Weitschies W, von Bergmann K, Siegmund W. Oswald S, et al. Among authors: remmler c. Clin Pharmacol Ther. 2006 Mar;79(3):206-17. doi: 10.1016/j.clpt.2005.11.004. Epub 2006 Feb 7. Clin Pharmacol Ther. 2006. PMID: 16513445
Non-response to antiepileptic pharmacotherapy is associated with the ABCC2 -24C>T polymorphism in young and adult patients with epilepsy.
Ufer M, Mosyagin I, Muhle H, Jacobsen T, Haenisch S, Häsler R, Faltraco F, Remmler C, von Spiczak S, Kroemer HK, Runge U, Boor R, Stephani U, Cascorbi I. Ufer M, et al. Among authors: remmler c. Pharmacogenet Genomics. 2009 May;19(5):353-62. doi: 10.1097/fpc.0b013e328329940b. Pharmacogenet Genomics. 2009. PMID: 19415824
Pharmacogenomics in acute coronary syndrome.
Remmler C, Cascorbi I. Remmler C, et al. Expert Opin Pharmacother. 2008 Feb;9(3):363-76. doi: 10.1517/14656566.9.3.363. Expert Opin Pharmacother. 2008. PMID: 18220488 Review.
A clinical trial on absorption and N-acetylation of oral and rectal mesalazine.
Dilger K, Trenk D, Rössle M, Cap M, Zähringer A, Wacheck V, Remmler C, Cascorbi I, Kreisel W, Novacek G. Dilger K, et al. Among authors: remmler c. Eur J Clin Invest. 2007 Jul;37(7):558-65. doi: 10.1111/j.1365-2362.2007.01809.x. Eur J Clin Invest. 2007. PMID: 17576207 Clinical Trial.