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Page 1
Regional brain mGlu5 receptor occupancy following single oral doses of mavoglurant as measured by [11C]-ABP688 PET imaging in healthy volunteers.
Streffer J, Treyer V, Buck A, Ametamey SM, Blagoev M, Maguire RP, Gautier A, Auberson YP, Schmidt ME, Vranesic IT, Gomez-Mancilla B, Gasparini F. Streffer J, et al. Among authors: auberson yp. Neuroimage. 2021 Apr 15;230:117785. doi: 10.1016/j.neuroimage.2021.117785. Epub 2021 Feb 2. Neuroimage. 2021. PMID: 33545349 Free article.
Reduced metabotropic glutamate receptor 5 density in major depression determined by [(11)C]ABP688 PET and postmortem study.
Deschwanden A, Karolewicz B, Feyissa AM, Treyer V, Ametamey SM, Johayem A, Burger C, Auberson YP, Sovago J, Stockmeier CA, Buck A, Hasler G. Deschwanden A, et al. Among authors: auberson yp. Am J Psychiatry. 2011 Jul;168(7):727-34. doi: 10.1176/appi.ajp.2011.09111607. Epub 2011 Apr 15. Am J Psychiatry. 2011. PMID: 21498461 Free PMC article.
Preclinical Evaluation of Benzazepine-Based PET Radioligands (R)- and (S)-11C-Me-NB1 Reveals Distinct Enantiomeric Binding Patterns and a Tightrope Walk Between GluN2B- and σ1-Receptor-Targeted PET Imaging.
Haider A, Herde AM, Krämer SD, Varisco J, Keller C, Frauenknecht K, Auberson YP, Temme L, Robaa D, Sippl W, Schibli R, Wünsch B, Mu L, Ametamey SM. Haider A, et al. Among authors: auberson yp. J Nucl Med. 2019 Aug;60(8):1167-1173. doi: 10.2967/jnumed.118.221051. Epub 2019 Jan 25. J Nucl Med. 2019. PMID: 30683765 Free PMC article.
ABP688, a novel selective and high affinity ligand for the labeling of mGlu5 receptors: identification, in vitro pharmacology, pharmacokinetic and biodistribution studies.
Hintermann S, Vranesic I, Allgeier H, Brülisauer A, Hoyer D, Lemaire M, Moenius T, Urwyler S, Whitebread S, Gasparini F, Auberson YP. Hintermann S, et al. Among authors: auberson yp. Bioorg Med Chem. 2007 Jan 15;15(2):903-14. doi: 10.1016/j.bmc.2006.10.038. Epub 2006 Oct 21. Bioorg Med Chem. 2007. PMID: 17110115
Synthesis, radiolabelling and biological characterization of (D)-7-iodo-N-(1-phosphonoethyl)-5-aminomethylquinoxaline-2,3-dione, a glycine-binding site antagonist of NMDA receptors.
Ametamey SM, Kokic M, Carrey-Rémy N, Bläuenstein P, Willmann M, Bischoff S, Schmutz M, Schubiger PA, Auberson YP. Ametamey SM, et al. Among authors: auberson yp. Bioorg Med Chem Lett. 2000 Jan 3;10(1):75-8. doi: 10.1016/s0960-894x(99)00576-4. Bioorg Med Chem Lett. 2000. PMID: 10636248
75 results