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The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis.
Dubois MJ, Bergeron S, Kim HJ, Dombrowski L, Perreault M, Fournès B, Faure R, Olivier M, Beauchemin N, Shulman GI, Siminovitch KA, Kim JK, Marette A. Dubois MJ, et al. Among authors: shulman gi. Nat Med. 2006 May;12(5):549-56. doi: 10.1038/nm1397. Epub 2006 Apr 16. Nat Med. 2006. PMID: 16617349
Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action.
Zabolotny JM, Haj FG, Kim YB, Kim HJ, Shulman GI, Kim JK, Neel BG, Kahn BB. Zabolotny JM, et al. Among authors: shulman gi. J Biol Chem. 2004 Jun 4;279(23):24844-51. doi: 10.1074/jbc.M310688200. Epub 2004 Mar 18. J Biol Chem. 2004. PMID: 15031294 Free article.
Mechanism of glucose intolerance in mice with dominant negative mutation of CEACAM1.
Park SY, Cho YR, Kim HJ, Hong EG, Higashimori T, Lee SJ, Goldberg IJ, Shulman GI, Najjar SM, Kim JK. Park SY, et al. Among authors: shulman gi. Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E517-24. doi: 10.1152/ajpendo.00077.2006. Epub 2006 Apr 25. Am J Physiol Endocrinol Metab. 2006. PMID: 16638824 Free article.
Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivo.
Hurov JB, Huang M, White LS, Lennerz J, Choi CS, Cho YR, Kim HJ, Prior JL, Piwnica-Worms D, Cantley LC, Kim JK, Shulman GI, Piwnica-Worms H. Hurov JB, et al. Among authors: shulman gi. Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5680-5. doi: 10.1073/pnas.0701179104. Epub 2007 Mar 19. Proc Natl Acad Sci U S A. 2007. PMID: 17372192 Free PMC article.
Mechanism of insulin resistance in A-ZIP/F-1 fatless mice.
Kim JK, Gavrilova O, Chen Y, Reitman ML, Shulman GI. Kim JK, et al. Among authors: shulman gi. J Biol Chem. 2000 Mar 24;275(12):8456-60. doi: 10.1074/jbc.275.12.8456. J Biol Chem. 2000. PMID: 10722680 Free article.
Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart.
Park SY, Kim HJ, Wang S, Higashimori T, Dong J, Kim YJ, Cline G, Li H, Prentki M, Shulman GI, Mitchell GA, Kim JK. Park SY, et al. Among authors: shulman gi. Am J Physiol Endocrinol Metab. 2005 Jul;289(1):E30-9. doi: 10.1152/ajpendo.00251.2004. Epub 2005 Feb 8. Am J Physiol Endocrinol Metab. 2005. PMID: 15701680 Free article.
601 results