Prestwich GD - Search Results

1

Synthesis and biological activity of phospholipase C-resistant analogues of phosphatidylinositol 4,5-bisphosphate.

Zhang H, Xu Y, Zhang Z, Liman ER, Prestwich GD. Zhang H, et al. Among authors: prestwich gd. J Am Chem Soc. 2006 May 3;128(17):5642-3. doi: 10.1021/ja060621d. J Am Chem Soc. 2006. PMID: 16637624 Free PMC article.

2

Chemical synthesis and molecular recognition of phosphatase-resistant analogues of phosphatidylinositol-3-phosphate.

Xu Y, Lee SA, Kutateladze TG, Sbrissa D, Shisheva A, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. J Am Chem Soc. 2006 Jan 25;128(3):885-97. doi: 10.1021/ja0554716. J Am Chem Soc. 2006. PMID: 16417379 Free PMC article.

3

Synthesis and biological activity of PTEN-resistant analogues of phosphatidylinositol 3,4,5-trisphosphate.

Zhang H, Markadieu N, Beauwens R, Erneux C, Prestwich GD. Zhang H, et al. Among authors: prestwich gd. J Am Chem Soc. 2006 Dec 27;128(51):16464-5. doi: 10.1021/ja065002j. J Am Chem Soc. 2006. PMID: 17177371 Free PMC article.

4

Stabilized phosphatidylinositol-5-phosphate analogues as ligands for the nuclear protein ING2: chemistry, biology, and molecular modeling.

Huang W, Zhang H, Davrazou F, Kutateladze TG, Shi X, Gozani O, Prestwich GD. Huang W, et al. Among authors: prestwich gd. J Am Chem Soc. 2007 May 23;129(20):6498-506. doi: 10.1021/ja070195b. Epub 2007 May 1. J Am Chem Soc. 2007. PMID: 17469822 Free PMC article.

5

Synthesis and biological activity of phosphatidylinositol-3,4,5-trisphosphorothioate.

Zhang H, Xu Y, Markadieu N, Beauwens R, Erneux C, Prestwich GD. Zhang H, et al. Among authors: prestwich gd. Bioorg Med Chem Lett. 2008 Jan 15;18(2):762-6. doi: 10.1016/j.bmcl.2007.11.041. Epub 2007 Nov 17. Bioorg Med Chem Lett. 2008. PMID: 18060773 Free PMC article.

6

Concise synthesis of acyl migration-blocked 1,1-difluorinated analogues of lysophosphatidic acid.

Xu Y, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. J Org Chem. 2002 Oct 4;67(20):7158-61. doi: 10.1021/jo0203037. J Org Chem. 2002. PMID: 12354017

7

Synthesis of chiral (alpha,alpha-difluoroalkyl)phosphonate analogues of (lyso)phosphatidic acid via hydrolytic kinetic resolution.

Xu Y, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. Org Lett. 2002 Nov 14;4(23):4021-4. doi: 10.1021/ol026684s. Org Lett. 2002. PMID: 12423076

8

Synthesis of monofluorinated analogues of lysophosphatidic acid.

Xu Y, Qian L, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. J Org Chem. 2003 Jun 27;68(13):5320-30. doi: 10.1021/jo020729l. J Org Chem. 2003. PMID: 12816494

9

Activation of mTOR signaling by novel fluoromethylene phosphonate analogues of phosphatidic acid.

Xu Y, Fang Y, Chen J, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. Bioorg Med Chem Lett. 2004 Mar 22;14(6):1461-4. doi: 10.1016/j.bmcl.2004.01.020. Bioorg Med Chem Lett. 2004. PMID: 15006382

10

Practical enantiospecific syntheses of lysobisphosphatidic acid and its analogues.

Jiang G, Xu Y, Prestwich GD. Jiang G, et al. Among authors: prestwich gd. J Org Chem. 2006 Feb 3;71(3):934-9. doi: 10.1021/jo051894e. J Org Chem. 2006. PMID: 16438504

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