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T-cell genetic modification for re-directed tumor recognition.
Cooper LJ, Kalos M, DiGiusto D, Brown C, Forman SJ, Raubitschek A, Jensen MC. Cooper LJ, et al. Cancer Chemother Biol Response Modif. 2005;22:293-324. doi: 10.1016/s0921-4410(04)22014-2. Cancer Chemother Biol Response Modif. 2005. PMID: 16110618 Review. No abstract available.
Antitransgene rejection responses contribute to attenuated persistence of adoptively transferred CD20/CD19-specific chimeric antigen receptor redirected T cells in humans.
Jensen MC, Popplewell L, Cooper LJ, DiGiusto D, Kalos M, Ostberg JR, Forman SJ. Jensen MC, et al. Biol Blood Marrow Transplant. 2010 Sep;16(9):1245-56. doi: 10.1016/j.bbmt.2010.03.014. Epub 2010 Mar 19. Biol Blood Marrow Transplant. 2010. PMID: 20304086 Free PMC article. Clinical Trial.
RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma.
DiGiusto DL, Krishnan A, Li L, Li H, Li S, Rao A, Mi S, Yam P, Stinson S, Kalos M, Alvarnas J, Lacey SF, Yee JK, Li M, Couture L, Hsu D, Forman SJ, Rossi JJ, Zaia JA. DiGiusto DL, et al. Sci Transl Med. 2010 Jun 16;2(36):36ra43. doi: 10.1126/scitranslmed.3000931. Sci Transl Med. 2010. PMID: 20555022 Free PMC article. Clinical Trial.
46 results