Dekker H - Search Results

1

P-glycoprotein drug efflux pump involved in the mechanisms of intrinsic drug resistance in various colon cancer cell lines. Evidence for a saturation of active daunorubicin transport.

Spoelstra EC, Dekker H, Schuurhuis GJ, Broxterman HJ, Lankelma J. Spoelstra EC, et al. Among authors: dekker h. Biochem Pharmacol. 1991 Feb 1;41(3):349-59. doi: 10.1016/0006-2952(91)90531-9. Biochem Pharmacol. 1991. PMID: 1671638

2

Probing daunorubicin accumulation defects in non-P-glycoprotein expressing multidrug-resistant cell lines using digitonin.

Versantvoort CH, Broxterman HJ, Feller N, Dekker H, Kuiper CM, Lankelma J. Versantvoort CH, et al. Among authors: dekker h. Int J Cancer. 1992 Apr 1;50(6):906-11. doi: 10.1002/ijc.2910500615. Int J Cancer. 1992. PMID: 1348241

3

Kinetics of daunorubicin transport by P-glycoprotein of intact cancer cells.

Spoelstra EC, Westerhoff HV, Dekker H, Lankelma J. Spoelstra EC, et al. Among authors: dekker h. Eur J Biochem. 1992 Jul 15;207(2):567-79. doi: 10.1111/j.1432-1033.1992.tb17083.x. Eur J Biochem. 1992. PMID: 1353020 Free article.

4

Evidence for daunomycin efflux from multidrug-resistant 2780AD human ovarian carcinoma cells against a concentration gradient.

Lankelma J, Spoelstra EC, Dekker H, Broxterman HJ. Lankelma J, et al. Among authors: dekker h. Biochim Biophys Acta. 1990 Dec 10;1055(3):217-22. doi: 10.1016/0167-4889(90)90035-c. Biochim Biophys Acta. 1990. PMID: 1979920

5

Measurement of in vitro cellular pharmacokinetics of 5-fluorouracil in human and rat cancer cell lines and rat hepatocytes using a flow-through system.

Spoelstra EC, Pinedo HM, Dekker H, Peters GJ, Lankelma J. Spoelstra EC, et al. Among authors: dekker h. Cancer Chemother Pharmacol. 1991;27(4):320-5. doi: 10.1007/BF00685119. Cancer Chemother Pharmacol. 1991. PMID: 1998989

6

The P-glycoprotein-mediated relative decrease in cytosolic free drug concentration is similar for several anthracyclines with varying lipophilicity.

Mülder HS, Dekker H, Pinedo HM, Lankelma J. Mülder HS, et al. Among authors: dekker h. Biochem Pharmacol. 1995 Sep 28;50(7):967-74. doi: 10.1016/0006-2952(95)00221-k. Biochem Pharmacol. 1995. PMID: 7575681

7

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.

Zaman GJ, Lankelma J, van Tellingen O, Beijnen J, Dekker H, Paulusma C, Oude Elferink RP, Baas F, Borst P. Zaman GJ, et al. Among authors: dekker h. Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7690-4. doi: 10.1073/pnas.92.17.7690. Proc Natl Acad Sci U S A. 1995. PMID: 7644478 Free PMC article.

8

The multidrug-resistance-reverser verapamil interferes with cellular P-glycoprotein-mediated pumping of daunorubicin as a non-competing substrate.

Spoelstra EC, Westerhoff HV, Pinedo HM, Dekker H, Lankelma J. Spoelstra EC, et al. Among authors: dekker h. Eur J Biochem. 1994 Apr 1;221(1):363-73. doi: 10.1111/j.1432-1033.1994.tb18748.x. Eur J Biochem. 1994. PMID: 7909520 Free article.

9

Daunorubicin efflux against a concentration gradient in non-P-glycoprotein multidrug-resistant lung-cancer cells.

Mülder HS, Lankelma J, Dekker H, Broxterman HJ, Pinedo HM. Mülder HS, et al. Among authors: dekker h. Int J Cancer. 1994 Oct 15;59(2):275-81. doi: 10.1002/ijc.2910590221. Int J Cancer. 1994. PMID: 7927929

10

Cortisol is transported by the multidrug resistance gene product P-glycoprotein.

van Kalken CK, Broxterman HJ, Pinedo HM, Feller N, Dekker H, Lankelma J, Giaccone G. van Kalken CK, et al. Among authors: dekker h. Br J Cancer. 1993 Feb;67(2):284-9. doi: 10.1038/bjc.1993.54. Br J Cancer. 1993. PMID: 8094292 Free PMC article.

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