Schreiber SL - Search Results

1

A robust small-molecule microarray platform for screening cell lysates.

Bradner JE, McPherson OM, Mazitschek R, Barnes-Seeman D, Shen JP, Dhaliwal J, Stevenson KE, Duffner JL, Park SB, Neuberg DS, Nghiem P, Schreiber SL, Koehler AN. Bradner JE, et al. Among authors: schreiber sl. Chem Biol. 2006 May;13(5):493-504. doi: 10.1016/j.chembiol.2006.03.004. Chem Biol. 2006. PMID: 16720270

2

(+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrest.

Hung DT, Chen J, Schreiber SL. Hung DT, et al. Among authors: schreiber sl. Chem Biol. 1996 Apr;3(4):287-93. doi: 10.1016/s1074-5521(96)90108-8. Chem Biol. 1996. PMID: 8807856

3

Understanding and controlling the cell cycle with natural products.

Hung DT, Jamison TF, Schreiber SL. Hung DT, et al. Among authors: schreiber sl. Chem Biol. 1996 Aug;3(8):623-39. doi: 10.1016/s1074-5521(96)90129-5. Chem Biol. 1996. PMID: 8807895 Review.

4

Proximity versus allostery: the role of regulated protein dimerization in biology.

Austin DJ, Crabtree GR, Schreiber SL. Austin DJ, et al. Among authors: schreiber sl. Chem Biol. 1994 Nov;1(3):131-6. doi: 10.1016/1074-5521(94)90002-7. Chem Biol. 1994. PMID: 9383382 Review.

5

Mechanistic studies of a signaling pathway activated by the organic dimerizer FK1012.

Pruschy MN, Spencer DM, Kapoor TM, Miyake H, Crabtree GR, Schreiber SL. Pruschy MN, et al. Among authors: schreiber sl. Chem Biol. 1994 Nov;1(3):163-72. doi: 10.1016/1074-5521(94)90006-x. Chem Biol. 1994. PMID: 9383386

6

A tricyclic ring system replaces the variable regions of peptides presented by three alleles of human MHC class I molecules.

Weiss GA, Collins EJ, Garboczi DN, Wiley DC, Schreiber SL. Weiss GA, et al. Among authors: schreiber sl. Chem Biol. 1995 Jun;2(6):401-7. doi: 10.1016/1074-5521(95)90221-x. Chem Biol. 1995. PMID: 9383442

7

Small-molecule control of insulin and PDGF receptor signaling and the role of membrane attachment.

Yang J, Symes K, Mercola M, Schreiber SL. Yang J, et al. Among authors: schreiber sl. Curr Biol. 1998 Jan 1;8(1):11-8. doi: 10.1016/s0960-9822(98)70015-6. Curr Biol. 1998. PMID: 9427627 Free article.

8

A miniaturized arrayed assay format for detecting small molecule-protein interactions in cells.

You AJ, Jackman RJ, Whitesides GM, Schreiber SL. You AJ, et al. Among authors: schreiber sl. Chem Biol. 1997 Dec;4(12):969-75. doi: 10.1016/s1074-5521(97)90305-7. Chem Biol. 1997. PMID: 9427662

9

Small molecule-dependent genetic selection in stochastic nanodroplets as a means of detecting protein-ligand interactions on a large scale.

Borchardt A, Liberles SD, Biggar SR, Crabtree GR, Schreiber SL. Borchardt A, et al. Among authors: schreiber sl. Chem Biol. 1997 Dec;4(12):961-8. doi: 10.1016/s1074-5521(97)90304-5. Chem Biol. 1997. PMID: 9427663

10

TGF-beta-signaling with small molecule FKBP12 antagonists that bind myristoylated FKBP12-TGF-beta type I receptor fusion proteins.

Stockwell BR, Schreiber SL. Stockwell BR, et al. Among authors: schreiber sl. Chem Biol. 1998 Jul;5(7):385-95. doi: 10.1016/s1074-5521(98)90072-2. Chem Biol. 1998. PMID: 9662508

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