Schofield CJ - Search Results

1

Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2).

McDonough MA, Li V, Flashman E, Chowdhury R, Mohr C, Liénard BM, Zondlo J, Oldham NJ, Clifton IJ, Lewis J, McNeill LA, Kurzeja RJ, Hewitson KS, Yang E, Jordan S, Syed RS, Schofield CJ. McDonough MA, et al. Among authors: schofield cj. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9814-9. doi: 10.1073/pnas.0601283103. Epub 2006 Jun 16. Proc Natl Acad Sci U S A. 2006. PMID: 16782814 Free PMC article.

2

Crystallization and preliminary X-ray diffraction studies on recombinant isopenicillin N synthase from Aspergillus nidulans.

Roach PL, Schofield CJ, Baldwin JE, Clifton IJ, Hajdu J. Roach PL, et al. Among authors: schofield cj. Protein Sci. 1995 May;4(5):1007-9. doi: 10.1002/pro.5560040521. Protein Sci. 1995. PMID: 7663335 Free PMC article.

3

Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes.

Roach PL, Clifton IJ, Fülöp V, Harlos K, Barton GJ, Hajdu J, Andersson I, Schofield CJ, Baldwin JE. Roach PL, et al. Among authors: schofield cj. Nature. 1995 Jun 22;375(6533):700-4. doi: 10.1038/375700a0. Nature. 1995. PMID: 7791906

4

Anaerobic crystallisation of an isopenicillin N synthase.Fe(II).substrate complex demonstrated by X-ray studies.

Roach PL, Clifton IJ, Hensgens CM, Shibata N, Long AJ, Strange RW, Hasnain SS, Schofield CJ, Baldwin JE, Hajdu J. Roach PL, et al. Among authors: schofield cj. Eur J Biochem. 1996 Dec 15;242(3):736-40. doi: 10.1111/j.1432-1033.1996.0736r.x. Eur J Biochem. 1996. PMID: 9022704 Free article.

5

Structure of a specific acyl-enzyme complex formed between beta-casomorphin-7 and porcine pancreatic elastase.

Wilmouth RC, Clifton IJ, Robinson CV, Roach PL, Aplin RT, Westwood NJ, Hajdu J, Schofield CJ. Wilmouth RC, et al. Among authors: schofield cj. Nat Struct Biol. 1997 Jun;4(6):456-62. doi: 10.1038/nsb0697-456. Nat Struct Biol. 1997. PMID: 9187653

6

Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation.

Roach PL, Clifton IJ, Hensgens CM, Shibata N, Schofield CJ, Hajdu J, Baldwin JE. Roach PL, et al. Among authors: schofield cj. Nature. 1997 Jun 19;387(6635):827-30. doi: 10.1038/42990. Nature. 1997. PMID: 9194566

7

Proteins of the penicillin biosynthesis pathway.

Schofield CJ, Baldwin JE, Byford MF, Clifton I, Hajdu J, Hensgens C, Roach P. Schofield CJ, et al. Curr Opin Struct Biol. 1997 Dec;7(6):857-64. doi: 10.1016/s0959-440x(97)80158-3. Curr Opin Struct Biol. 1997. PMID: 9434907 Review.

8

Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex.

Wilmouth RC, Westwood NJ, Anderson K, Brownlee W, Claridge TD, Clifton IJ, Pritchard GJ, Aplin RT, Schofield CJ. Wilmouth RC, et al. Among authors: schofield cj. Biochemistry. 1998 Dec 15;37(50):17506-13. doi: 10.1021/bi9816249. Biochemistry. 1998. PMID: 9860865

9

'pH-jump' crystallographic analyses of gamma-lactam-porcine pancreatic elastase complexes.

Wright PA, Wilmouth RC, Clifton IJ, Schofield CJ. Wright PA, et al. Among authors: schofield cj. Biochem J. 2000 Oct 15;351 Pt 2(Pt 2):335-40. Biochem J. 2000. PMID: 11023818 Free PMC article.

10

Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase. The role of arginine 258.

Lee HJ, Lloyd MD, Clifton IJ, Harlos K, Dubus A, Baldwin JE, Frere JM, Schofield CJ. Lee HJ, et al. Among authors: schofield cj. J Biol Chem. 2001 May 25;276(21):18290-5. doi: 10.1074/jbc.M100085200. Epub 2001 Feb 21. J Biol Chem. 2001. PMID: 11279000 Free article.

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