Wright JL - Search Results

1

3-arylimino-2-indolones are potent and selective galanin GAL3 receptor antagonists.

Konkel MJ, Lagu B, Boteju LW, Jimenez H, Noble S, Walker MW, Chandrasena G, Blackburn TP, Nikam SS, Wright JL, Kornberg BE, Gregory T, Pugsley TA, Akunne H, Zoski K, Wise LD. Konkel MJ, et al. Among authors: wright jl. J Med Chem. 2006 Jun 29;49(13):3757-8. doi: 10.1021/jm060001n. J Med Chem. 2006. PMID: 16789730

2

Design, synthesis, and evaluation of chromen-2-ones as potent and selective human dopamine D4 antagonists.

Kesten SR, Heffner TG, Johnson SJ, Pugsley TA, Wright JL, Wise LD. Kesten SR, et al. Among authors: wright jl. J Med Chem. 1999 Sep 9;42(18):3718-25. doi: 10.1021/jm990266k. J Med Chem. 1999. PMID: 10479303

3

Subtype selective NMDA receptor antagonists: evaluation of some novel alkynyl analogues.

Kornberg BE, Nikam SS, Wright JL, Kesten SR, Meltzer LT, Coughenour L, Barr B, Serpa KA, McCormick J. Kornberg BE, et al. Among authors: wright jl. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1213-6. doi: 10.1016/j.bmcl.2003.12.049. Bioorg Med Chem Lett. 2004. PMID: 14980668

4

Subtype-selective N-methyl-D-aspartate receptor antagonists: synthesis and biological evaluation of 1-(arylalkynyl)-4-benzylpiperidines.

Wright JL, Gregory TF, Bigge CF, Boxer PA, Serpa K, Meltzer LT, Wise LD, Cai SX, Hawkinson JE, Konkoy CS, Whittemore ER, Woodward RM, Zhou ZL. Wright JL, et al. J Med Chem. 1999 Jul 1;42(13):2469-77. doi: 10.1021/jm990148x. J Med Chem. 1999. PMID: 10395488

5

Parallel synthesis of a series of subtype-selective NMDA receptor antagonists.

Gregory TF, Wright JL, Wise LD, Meltzer LT, Serpa KA, Konkoy CS, Whittemore ER, Woodward RM. Gregory TF, et al. Among authors: wright jl. Bioorg Med Chem Lett. 2000 Mar 20;10(6):527-9. doi: 10.1016/s0960-894x(00)00035-4. Bioorg Med Chem Lett. 2000. PMID: 10741546

6

Subtype-selective N-methyl-D-aspartate receptor antagonists: synthesis and biological evaluation of 1-(heteroarylalkynyl)-4-benzylpiperidines.

Wright JL, Gregory TF, Kesten SR, Boxer PA, Serpa KA, Meltzer LT, Wise LD, Espitia SA, Konkoy CS, Whittemore ER, Woodward RM. Wright JL, et al. J Med Chem. 2000 Sep 7;43(18):3408-19. doi: 10.1021/jm000023o. J Med Chem. 2000. PMID: 10978188

7

Discovery of subtype-selective NMDA receptor ligands: 4-benzyl-1-piperidinylalkynylpyrroles, pyrazoles and imidazoles as NR1A/2B antagonists.

Wright JL, Gregory TF, Boxer PA, Meltzer LT, Serpa KA, Wise LD. Wright JL, et al. Bioorg Med Chem Lett. 1999 Oct 4;9(19):2815-8. doi: 10.1016/s0960-894x(99)00482-5. Bioorg Med Chem Lett. 1999. PMID: 10522697

8

Identification, characterization and pharmacological profile of three metabolites of (R)-(+)-1,2,3,6-tetrahydro-4-phenyl-1-[(3-phenylcyclohexen-1- yl)methyl]pyridine (CI-1007), a dopamine autoreceptor agonist and potential antipsychotic agent.

Wright JL, Downing DM, Feng MR, Hayes RN, Heffner TG, MacKenzie RG, Meltzer LT, Pugsley TA, Wise LD. Wright JL, et al. J Med Chem. 1995 Dec 22;38(26):5007-14. doi: 10.1021/jm00026a007. J Med Chem. 1995. PMID: 8544176

9

Pharmacological characterization of PD 152255, a novel dimeric benzimidazole dopamine D3 antagonist.

Corbin AE, Pugsley TA, Akunne HC, Whetzel SZ, Zoski KT, Georgic LM, Nelson CB, Wright JL, Wise LD, Heffner TG. Corbin AE, et al. Among authors: wright jl. Pharmacol Biochem Behav. 1998 Feb;59(2):487-93. doi: 10.1016/s0091-3057(97)00442-5. Pharmacol Biochem Behav. 1998. PMID: 9476999

10

Synthesis of N-substituted 4-(4-hydroxyphenyl)piperidines, 4-(4-hydroxybenzyl)piperidines, and (+/-)-3-(4-hydroxyphenyl)pyrrolidines: selective antagonists at the 1A/2B NMDA receptor subtype.

Guzikowski AP, Tamiz AP, Acosta-Burruel M, Hong-Bae S, Cai SX, Hawkinson JE, Keana JF, Kesten SR, Shipp CT, Tran M, Whittemore ER, Woodward RM, Wright JL, Zhou ZL. Guzikowski AP, et al. Among authors: wright jl. J Med Chem. 2000 Mar 9;43(5):984-94. doi: 10.1021/jm990428c. J Med Chem. 2000. PMID: 10715162

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