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Page 1
MicroRNA-143 regulates adipocyte differentiation.
Esau C, Kang X, Peralta E, Hanson E, Marcusson EG, Ravichandran LV, Sun Y, Koo S, Perera RJ, Jain R, Dean NM, Freier SM, Bennett CF, Lollo B, Griffey R. Esau C, et al. Among authors: freier sm. J Biol Chem. 2004 Dec 10;279(50):52361-5. doi: 10.1074/jbc.C400438200. Epub 2004 Oct 25. J Biol Chem. 2004. PMID: 15504739 Free article.
Pseudo--half-knot formation with RNA.
Ecker DJ, Vickers TA, Bruice TW, Freier SM, Jenison RD, Manoharan M, Zounes M. Ecker DJ, et al. Among authors: freier sm. Science. 1992 Aug 14;257(5072):958-61. doi: 10.1126/science.1502560. Science. 1992. PMID: 1502560
Fully modified 2' MOE oligonucleotides redirect polyadenylation.
Vickers TA, Wyatt JR, Burckin T, Bennett CF, Freier SM. Vickers TA, et al. Among authors: freier sm. Nucleic Acids Res. 2001 Mar 15;29(6):1293-9. doi: 10.1093/nar/29.6.1293. Nucleic Acids Res. 2001. PMID: 11238995 Free PMC article.
Identification and characterization of modified antisense oligonucleotides targeting DMPK in mice and nonhuman primates for the treatment of myotonic dystrophy type 1.
Pandey SK, Wheeler TM, Justice SL, Kim A, Younis HS, Gattis D, Jauvin D, Puymirat J, Swayze EE, Freier SM, Bennett CF, Thornton CA, MacLeod AR. Pandey SK, et al. Among authors: freier sm. J Pharmacol Exp Ther. 2015 Nov;355(2):329-40. doi: 10.1124/jpet.115.226969. Epub 2015 Sep 1. J Pharmacol Exp Ther. 2015. PMID: 26330536 Free PMC article.
Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts.
Burel SA, Hart CE, Cauntay P, Hsiao J, Machemer T, Katz M, Watt A, Bui HH, Younis H, Sabripour M, Freier SM, Hung G, Dan A, Prakash TP, Seth PP, Swayze EE, Bennett CF, Crooke ST, Henry SP. Burel SA, et al. Among authors: freier sm. Nucleic Acids Res. 2016 Mar 18;44(5):2093-109. doi: 10.1093/nar/gkv1210. Epub 2015 Nov 8. Nucleic Acids Res. 2016. PMID: 26553810 Free PMC article.
98 results