Sowa H - Search Results

1

Expression and functional analysis of menin in a multiple endocrine neoplasia type 1 (MEN1) patient with somatic loss of heterozygosity in chromosome 11q13 and unidentified germline mutation of the MEN1 gene.

Naito J, Kaji H, Sowa H, Kitazawa R, Kitazawa S, Tsukada T, Hendy GN, Sugimoto T, Chihara K. Naito J, et al. Among authors: sowa h. Endocrine. 2006 Jun;29(3):485-90. doi: 10.1385/ENDO:29:3:485. Endocrine. 2006. PMID: 16943588

2

Inactivation of menin, the product of the multiple endocrine neoplasia type 1 gene, inhibits the commitment of multipotential mesenchymal stem cells into the osteoblast lineage.

Sowa H, Kaji H, Canaff L, Hendy GN, Tsukamoto T, Yamaguchi T, Miyazono K, Sugimoto T, Chihara K. Sowa H, et al. J Biol Chem. 2003 Jun 6;278(23):21058-69. doi: 10.1074/jbc.M302044200. Epub 2003 Mar 20. J Biol Chem. 2003. PMID: 12649288 Free article.

3

Functional giant parathyroid cyst with high concentration of CA19-9 in cystic fluid.

Makino T, Sugimoto T, Kaji H, Yamaguchi T, Kitazawa R, Yamauchi M, Sowa H, Chen Q, Nomura R, Tsukamoto T, Chihara K. Makino T, et al. Among authors: sowa h. Endocr J. 2003 Apr;50(2):215-9. doi: 10.1507/endocrj.50.215. Endocr J. 2003. PMID: 12803242 Free article.

4

Trial to predict malignancy of affected parathyroid glands in primary hyperparathyroidism.

Chen Q, Kaji H, Nomura R, Sowa H, Yamauchi M, Tsukamoto T, Yamaguchi T, Kobayashi A, Sugimoto T, Chihara K. Chen Q, et al. Among authors: sowa h. Endocr J. 2003 Oct;50(5):527-34. doi: 10.1507/endocrj.50.527. Endocr J. 2003. PMID: 14614208 Free article.

5

Menin inactivation leads to loss of transforming growth factor beta inhibition of parathyroid cell proliferation and parathyroid hormone secretion.

Sowa H, Kaji H, Kitazawa R, Kitazawa S, Tsukamoto T, Yano S, Tsukada T, Canaff L, Hendy GN, Sugimoto T, Chihara K. Sowa H, et al. Cancer Res. 2004 Mar 15;64(6):2222-8. doi: 10.1158/0008-5472.can-03-3334. Cancer Res. 2004. PMID: 15026366

6

Menin suppresses osteoblast differentiation by antagonizing the AP-1 factor, JunD.

Naito J, Kaji H, Sowa H, Hendy GN, Sugimoto T, Chihara K. Naito J, et al. Among authors: sowa h. J Biol Chem. 2005 Feb 11;280(6):4785-91. doi: 10.1074/jbc.M408143200. Epub 2004 Nov 23. J Biol Chem. 2005. PMID: 15563473 Free article.

We have shown previously that menin is required for the commitment of multipotential mesenchymal stem cells into the osteoblast lineage in part by interacting with the bone morphogenetic protein (BMP)-2 signaling molecules Smad1/5, and the key osteoblast transcriptional regulator …

We have shown previously that menin is required for the commitment of multipotential mesenchymal stem cells into the osteoblast lineage in p …

7

Menin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2.

Sowa H, Kaji H, Hendy GN, Canaff L, Komori T, Sugimoto T, Chihara K. Sowa H, et al. J Biol Chem. 2004 Sep 24;279(39):40267-75. doi: 10.1074/jbc.M401312200. Epub 2004 May 18. J Biol Chem. 2004. PMID: 15150273 Free article.

Menin, the product of the multiple endocrine neoplasia type 1 (MEN1) gene, is required for commitment of multipotential mesenchymal stem cells to the osteoblast lineage, however, it inhibits their later differentiation (Sowa, H., Kaji, H., Canaff, L., Hendy, …

Menin, the product of the multiple endocrine neoplasia type 1 (MEN1) gene, is required for commitment of multipotential mesenchymal stem cel …

8

Serum soluble factors induce the proliferation, alkaline phosphatase activity and transforming growth factor-beta signal in osteoblastic cells in the patient with hepatitis C-associated osteosclerosis.

Kaji H, Naito J, Sowa H, Sugimoto T, Chihara K. Kaji H, et al. Among authors: sowa h. Exp Clin Endocrinol Diabetes. 2006 Nov;114(10):599-604. doi: 10.1055/s-2006-924399. Exp Clin Endocrinol Diabetes. 2006. PMID: 17177144

9

Expression of parathyroid hormone-related protein (PTHrP) in multiple myeloma.

Kitazawa R, Kitazawa S, Kajimoto K, Sowa H, Sugimoto T, Matsui T, Chihara K, Maeda S. Kitazawa R, et al. Among authors: sowa h. Pathol Int. 2002 Jan;52(1):63-8. doi: 10.1046/j.1440-1827.2002.01314.x. Pathol Int. 2002. PMID: 11940209 Review.

10

Plasma lipids and osteoporosis in postmenopausal women.

Yamaguchi T, Sugimoto T, Yano S, Yamauchi M, Sowa H, Chen Q, Chihara K. Yamaguchi T, et al. Among authors: sowa h. Endocr J. 2002 Apr;49(2):211-7. doi: 10.1507/endocrj.49.211. Endocr J. 2002. PMID: 12081241 Free article.

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