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Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritis.
Wessels JA, Kooloos WM, De Jonge R, De Vries-Bouwstra JK, Allaart CF, Linssen A, Collee G, De Sonnaville P, Lindemans J, Huizinga TW, Guchelaar HJ. Wessels JA, et al. Among authors: guchelaar hj. Arthritis Rheum. 2006 Sep;54(9):2830-9. doi: 10.1002/art.22032. Arthritis Rheum. 2006. PMID: 16947783 Free article. Clinical Trial.
Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.
Wessels JA, de Vries-Bouwstra JK, Heijmans BT, Slagboom PE, Goekoop-Ruiterman YP, Allaart CF, Kerstens PJ, van Zeben D, Breedveld FC, Dijkmans BA, Huizinga TW, Guchelaar HJ. Wessels JA, et al. Among authors: guchelaar hj. Arthritis Rheum. 2006 Apr;54(4):1087-95. doi: 10.1002/art.21726. Arthritis Rheum. 2006. PMID: 16572443 Free article.
Genetic markers of treatment response in rheumatoid arthritis.
Wesoly J, Wessels JA, Guchelaar HJ, Huizinga TW. Wesoly J, et al. Among authors: guchelaar hj. Curr Rheumatol Rep. 2006 Oct;8(5):369-77. doi: 10.1007/s11926-006-0068-5. Curr Rheumatol Rep. 2006. PMID: 16973111 Review.
Exploratory analysis of four polymorphisms in human GGH and FPGS genes and their effect in methotrexate-treated rheumatoid arthritis patients.
van der Straaten RJ, Wessels JA, de Vries-Bouwstra JK, Goekoop-Ruiterman YP, Allaart CF, Bogaartz J, Tiller M, Huizinga TW, Guchelaar HJ. van der Straaten RJ, et al. Among authors: guchelaar hj. Pharmacogenomics. 2007 Feb;8(2):141-50. doi: 10.2217/14622416.8.2.141. Pharmacogenomics. 2007. PMID: 17286537 Clinical Trial.
Translating pharmacogenomics: challenges on the road to the clinic.
Swen JJ, Huizinga TW, Gelderblom H, de Vries EG, Assendelft WJ, Kirchheiner J, Guchelaar HJ. Swen JJ, et al. Among authors: guchelaar hj. PLoS Med. 2007 Aug;4(8):e209. doi: 10.1371/journal.pmed.0040209. PLoS Med. 2007. PMID: 17696640 Free PMC article. Review.
Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity.
van Erp NP, Eechoute K, van der Veldt AA, Haanen JB, Reyners AK, Mathijssen RH, Boven E, van der Straaten T, Baak-Pablo RF, Wessels JA, Guchelaar HJ, Gelderblom H. van Erp NP, et al. Among authors: guchelaar hj. J Clin Oncol. 2009 Sep 10;27(26):4406-12. doi: 10.1200/JCO.2008.21.7679. Epub 2009 Aug 10. J Clin Oncol. 2009. PMID: 19667267
469 results