Andreu JM - Search Results

1

Farnesyltransferase inhibitors reverse taxane resistance.

Marcus AI, O'Brate AM, Buey RM, Zhou J, Thomas S, Khuri FR, Andreu JM, Díaz F, Giannakakou P. Marcus AI, et al. Among authors: andreu jm. Cancer Res. 2006 Sep 1;66(17):8838-46. doi: 10.1158/0008-5472.CAN-06-0699. Cancer Res. 2006. PMID: 16951201 Free PMC article.

2

Peloruside A does not bind to the taxoid site on beta-tubulin and retains its activity in multidrug-resistant cell lines.

Gaitanos TN, Buey RM, Díaz JF, Northcote PT, Teesdale-Spittle P, Andreu JM, Miller JH. Gaitanos TN, et al. Among authors: andreu jm. Cancer Res. 2004 Aug 1;64(15):5063-7. doi: 10.1158/0008-5472.CAN-04-0771. Cancer Res. 2004. PMID: 15289305

3

The microtubule stabilizing agent laulimalide does not bind in the taxoid site, kills cells resistant to paclitaxel and epothilones, and may not require its epoxide moiety for activity.

Pryor DE, O'Brate A, Bilcer G, Díaz JF, Wang Y, Wang Y, Kabaki M, Jung MK, Andreu JM, Ghosh AK, Giannakakou P, Hamel E. Pryor DE, et al. Among authors: andreu jm. Biochemistry. 2002 Jul 23;41(29):9109-15. doi: 10.1021/bi020211b. Biochemistry. 2002. PMID: 12119025

4

Interaction of epothilone analogs with the paclitaxel binding site: relationship between binding affinity, microtubule stabilization, and cytotoxicity.

Buey RM, Díaz JF, Andreu JM, O'Brate A, Giannakakou P, Nicolaou KC, Sasmal PK, Ritzén A, Namoto K. Buey RM, et al. Among authors: andreu jm. Chem Biol. 2004 Feb;11(2):225-36. doi: 10.1016/j.chembiol.2004.01.014. Chem Biol. 2004. PMID: 15123284

5

Microtubule interactions with chemically diverse stabilizing agents: thermodynamics of binding to the paclitaxel site predicts cytotoxicity.

Buey RM, Barasoain I, Jackson E, Meyer A, Giannakakou P, Paterson I, Mooberry S, Andreu JM, Díaz JF. Buey RM, et al. Among authors: andreu jm. Chem Biol. 2005 Dec;12(12):1269-79. doi: 10.1016/j.chembiol.2005.09.010. Chem Biol. 2005. PMID: 16356844

6

The nucleotide switch of tubulin and microtubule assembly: a polymerization-driven structural change.

Buey RM, Díaz JF, Andreu JM. Buey RM, et al. Among authors: andreu jm. Biochemistry. 2006 May 16;45(19):5933-8. doi: 10.1021/bi060334m. Biochemistry. 2006. PMID: 16681364

7

Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites.

Buey RM, Calvo E, Barasoain I, Pineda O, Edler MC, Matesanz R, Cerezo G, Vanderwal CD, Day BW, Sorensen EJ, López JA, Andreu JM, Hamel E, Díaz JF. Buey RM, et al. Among authors: andreu jm. Nat Chem Biol. 2007 Feb;3(2):117-25. doi: 10.1038/nchembio853. Epub 2007 Jan 7. Nat Chem Biol. 2007. PMID: 17206139 Free article.

8

NMR determination of the bioactive conformation of peloruside A bound to microtubules.

Jiménez-Barbero J, Canales A, Northcote PT, Buey RM, Andreu JM, Díaz JF. Jiménez-Barbero J, et al. Among authors: andreu jm. J Am Chem Soc. 2006 Jul 12;128(27):8757-65. doi: 10.1021/ja0580237. J Am Chem Soc. 2006. PMID: 16819869

9

Mapping flexibility and the assembly switch of cell division protein FtsZ by computational and mutational approaches.

Martín-Galiano AJ, Buey RM, Cabezas M, Andreu JM. Martín-Galiano AJ, et al. Among authors: andreu jm. J Biol Chem. 2010 Jul 16;285(29):22554-65. doi: 10.1074/jbc.M110.117127. Epub 2010 May 13. J Biol Chem. 2010. PMID: 20472561 Free PMC article.

10

Induction of apoptosis in leukemic cells by the reversible microtubule-disrupting agent 2-methoxy-5-(2',3',4'-trimethoxyphenyl)-2,4,6-cycloheptatrien-1 -one: protection by Bcl-2 and Bcl-X(L) and cell cycle arrest.

Gajate C, Barasoain I, Andreu JM, Mollinedo F. Gajate C, et al. Among authors: andreu jm. Cancer Res. 2000 May 15;60(10):2651-9. Cancer Res. 2000. PMID: 10825137

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