Cragg MS - Search Results

1

Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic.

Kuroda J, Puthalakath H, Cragg MS, Kelly PN, Bouillet P, Huang DC, Kimura S, Ottmann OG, Druker BJ, Villunger A, Roberts AW, Strasser A. Kuroda J, et al. Among authors: cragg ms. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14907-12. doi: 10.1073/pnas.0606176103. Epub 2006 Sep 22. Proc Natl Acad Sci U S A. 2006. PMID: 16997913 Free PMC article.

2

Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics.

Cragg MS, Kuroda J, Puthalakath H, Huang DC, Strasser A. Cragg MS, et al. PLoS Med. 2007 Oct;4(10):1681-89; discussion 1690. doi: 10.1371/journal.pmed.0040316. PLoS Med. 2007. PMID: 17973573 Free PMC article.

3

Treatment of B-RAF mutant human tumor cells with a MEK inhibitor requires Bim and is enhanced by a BH3 mimetic.

Cragg MS, Jansen ES, Cook M, Harris C, Strasser A, Scott CL. Cragg MS, et al. J Clin Invest. 2008 Nov;118(11):3651-9. doi: 10.1172/JCI35437. Epub 2008 Oct 23. J Clin Invest. 2008. PMID: 18949058 Free PMC article.

4

Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics.

Cragg MS, Harris C, Strasser A, Scott CL. Cragg MS, et al. Nat Rev Cancer. 2009 May;9(5):321-6. doi: 10.1038/nrc2615. Epub 2009 Apr 3. Nat Rev Cancer. 2009. PMID: 19343035 Review.

5

Maximal killing of lymphoma cells by DNA damage-inducing therapy requires not only the p53 targets Puma and Noxa, but also Bim.

Happo L, Cragg MS, Phipson B, Haga JM, Jansen ES, Herold MJ, Dewson G, Michalak EM, Vandenberg CJ, Smyth GK, Strasser A, Cory S, Scott CL. Happo L, et al. Among authors: cragg ms. Blood. 2010 Dec 9;116(24):5256-67. doi: 10.1182/blood-2010-04-280818. Epub 2010 Sep 9. Blood. 2010. PMID: 20829369 Free PMC article.

6

BCR-signaling-induced cell death demonstrates dependency on multiple BH3-only proteins in a murine model of B-cell lymphoma.

Carter MJ, Cox KL, Blakemore SJ, Bogdanov YD, Happo L, Scott CL, Strasser A, Packham GK, Cragg MS. Carter MJ, et al. Among authors: cragg ms. Cell Death Differ. 2016 Feb;23(2):303-12. doi: 10.1038/cdd.2015.97. Epub 2015 Jul 17. Cell Death Differ. 2016. PMID: 26184912 Free PMC article.

7

Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis.

Michalak EM, Jansen ES, Happo L, Cragg MS, Tai L, Smyth GK, Strasser A, Adams JM, Scott CL. Michalak EM, et al. Among authors: cragg ms. Cell Death Differ. 2009 May;16(5):684-96. doi: 10.1038/cdd.2008.195. Epub 2009 Jan 16. Cell Death Differ. 2009. PMID: 19148184 Free PMC article.

8

CML cells expressing the TEL/MDS1/EVI1 fusion are resistant to imatinib-induced apoptosis through inhibition of BAD, but are resensitized with ABT-737.

Shimada K, Tomita A, Minami Y, Abe A, Hind CK, Kiyoi H, Cragg MS, Naoe T. Shimada K, et al. Among authors: cragg ms. Exp Hematol. 2012 Sep;40(9):724-737.e2. doi: 10.1016/j.exphem.2012.05.007. Epub 2012 May 24. Exp Hematol. 2012. PMID: 22634393 Free article.

9

PI3Kδ inhibition elicits anti-leukemic effects through Bim-dependent apoptosis.

Carter MJ, Cox KL, Blakemore SJ, Turaj AH, Oldham RJ, Dahal LN, Tannheimer S, Forconi F, Packham G, Cragg MS. Carter MJ, et al. Among authors: cragg ms. Leukemia. 2017 Jun;31(6):1423-1433. doi: 10.1038/leu.2016.333. Epub 2016 Nov 15. Leukemia. 2017. PMID: 27843137 Free PMC article.

10

Death by a thousand knives: Multiple BH3-only proteins are required for maximal apoptosis triggered through the BCR.

Carter MJ, Cragg MS. Carter MJ, et al. Among authors: cragg ms. Mol Cell Oncol. 2015 Aug 27;3(2):e1084444. doi: 10.1080/23723556.2015.1084444. eCollection 2016 Mar. Mol Cell Oncol. 2015. PMID: 27308607 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

206 results

Search Page

Filters