Kobayashi K - Search Results

1

Identification of human cytochrome p450 isozymes involved in diphenhydramine N-demethylation.

Akutsu T, Kobayashi K, Sakurada K, Ikegaya H, Furihata T, Chiba K. Akutsu T, et al. Among authors: kobayashi k. Drug Metab Dispos. 2007 Jan;35(1):72-8. doi: 10.1124/dmd.106.012088. Epub 2006 Oct 4. Drug Metab Dispos. 2007. PMID: 17020955

2

Substrate specificity for rat cytochrome P450 (CYP) isoforms: screening with cDNA-expressed systems of the rat.

Kobayashi K, Urashima K, Shimada N, Chiba K. Kobayashi K, et al. Biochem Pharmacol. 2002 Mar 1;63(5):889-96. doi: 10.1016/s0006-2952(01)00843-7. Biochem Pharmacol. 2002. PMID: 11911841

3

Effects of G169R and P34S substitutions produced by mutations of CYP2D6*14 on the functional properties of CYP2D6 expressed in V79 cells.

Shiraishi T, Hosokawa M, Kobayashi K, Tainaka H, Yamaura Y, Taguchi M, Chiba K. Shiraishi T, et al. Among authors: kobayashi k. Drug Metab Dispos. 2002 Nov;30(11):1201-5. doi: 10.1124/dmd.30.11.1201. Drug Metab Dispos. 2002. PMID: 12386125

4

Selectivities of human cytochrome P450 inhibitors toward rat P450 isoforms: study with cDNA-expressed systems of the rat.

Kobayashi K, Urashima K, Shimada N, Chiba K. Kobayashi K, et al. Drug Metab Dispos. 2003 Jul;31(7):833-6. doi: 10.1124/dmd.31.7.833. Drug Metab Dispos. 2003. PMID: 12814958

5

Metabolism of medroxyprogesterone acetate (MPA) via CYP enzymes in vitro and effect of MPA on bleeding time in female rats in dependence on CYP activity in vivo.

Mimura N, Kobayashi K, Nakamura Y, Shimada N, Hosokawa M, Chiba K. Mimura N, et al. Among authors: kobayashi k. Life Sci. 2003 Nov 7;73(25):3201-12. doi: 10.1016/j.lfs.2003.05.004. Life Sci. 2003. PMID: 14561525

6

Catalytic roles of CYP2C9 and its variants (CYP2C9*2 and CYP2C9*3) in lornoxicam 5'-hydroxylation.

Iida I, Miyata A, Arai M, Hirota M, Akimoto M, Higuchi S, Kobayashi K, Chiba K. Iida I, et al. Among authors: kobayashi k. Drug Metab Dispos. 2004 Jan;32(1):7-9. doi: 10.1124/dmd.32.1.7. Drug Metab Dispos. 2004. PMID: 14709614

7

Key structural features of ligands for activation of human pregnane X receptor.

Kobayashi K, Yamagami S, Higuchi T, Hosokawa M, Chiba K. Kobayashi K, et al. Drug Metab Dispos. 2004 Apr;32(4):468-72. doi: 10.1124/dmd.32.4.468. Drug Metab Dispos. 2004. PMID: 15039302

8

Pharmacogenetic roles of CYP2C19 and CYP2B6 in the metabolism of R- and S-mephobarbital in humans.

Kobayashi K, Morita J, Chiba K, Wanibuchi A, Kimura M, Irie S, Urae A, Ishizaki T. Kobayashi K, et al. Pharmacogenetics. 2004 Aug;14(8):549-56. doi: 10.1097/01.fpc.0000114764.78957.22. Pharmacogenetics. 2004. PMID: 15284537

9

Allelic expression imbalance of the human CYP3A4 gene and individual phenotypic status.

Hirota T, Ieiri I, Takane H, Maegawa S, Hosokawa M, Kobayashi K, Chiba K, Nanba E, Oshimura M, Sato T, Higuchi S, Otsubo K. Hirota T, et al. Among authors: kobayashi k. Hum Mol Genet. 2004 Dec 1;13(23):2959-69. doi: 10.1093/hmg/ddh313. Epub 2004 Sep 30. Hum Mol Genet. 2004. PMID: 15459178

10

A novel single nucleotide polymorphism (SNP) of the CYP2C19 gene in a Japanese subject with lowered capacity of mephobarbital 4'-hydroxylation.

Morita J, Kobayashi K, Wanibuchi A, Kimura M, Irie S, Ishizaki T, Chiba K. Morita J, et al. Among authors: kobayashi k. Drug Metab Pharmacokinet. 2004 Jun;19(3):236-8. doi: 10.2133/dmpk.19.236. Drug Metab Pharmacokinet. 2004. PMID: 15499191 Free article.

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