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Aldehyde oxidase 1 is highly abundant in hepatic steatosis and is downregulated by adiponectin and fenofibric acid in hepatocytes in vitro.
Neumeier M, Weigert J, Schäffler A, Weiss TS, Schmidl C, Büttner R, Bollheimer C, Aslanidis C, Schölmerich J, Buechler C. Neumeier M, et al. Among authors: schaffler a. Biochem Biophys Res Commun. 2006 Nov 24;350(3):731-5. doi: 10.1016/j.bbrc.2006.09.101. Epub 2006 Sep 27. Biochem Biophys Res Commun. 2006. PMID: 17022944
The Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is not associated with obesity or type 2 diabetes mellitus in a large population-based Caucasian cohort.
Büettner R, Schäffler A, Arndt H, Rogler G, Nusser J, Zietz B, Enger I, Hügl S, Cuk A, Schölmerich J, Palitzsch KD. Büettner R, et al. Among authors: schaffler a. J Clin Endocrinol Metab. 1998 Aug;83(8):2892-7. doi: 10.1210/jcem.83.8.5004. J Clin Endocrinol Metab. 1998. PMID: 9709965
The human apM-1, an adipocyte-specific gene linked to the family of TNF's and to genes expressed in activated T cells, is mapped to chromosome 1q21.3-q23, a susceptibility locus identified for familial combined hyperlipidaemia (FCH).
Schäffler A, Orsó E, Palitzsch KD, Büchler C, Drobnik W, Fürst A, Schölmerich J, Schmitz G. Schäffler A, et al. Biochem Biophys Res Commun. 1999 Jul 5;260(2):416-25. doi: 10.1006/bbrc.1999.0865. Biochem Biophys Res Commun. 1999. PMID: 10403784
Frequency and significance of the A-->G (-3826) polymorphism in the promoter of the gene for uncoupling protein-1 with regard to metabolic parameters and adipocyte transcription factor binding in a large population-based Caucasian cohort.
Schäffler A, Palitzsch KD, Watzlawek E, Drobnik W, Schwer H, Schölmerich J, Schmitz G. Schäffler A, et al. Eur J Clin Invest. 1999 Sep;29(9):770-9. doi: 10.1046/j.1365-2362.1999.00529.x. Eur J Clin Invest. 1999. PMID: 10469165
Identification of a new missense mutation (Gly95Glu) in a highly conserved codon within the high-mobility group box of the sex-determining region Y gene: report on a 46,XY female with gonadal dysgenesis and yolk-sac tumor.
Schäffler A, Barth N, Winkler K, Zietz B, Rümmele P, Knüchel R, Schölmerich J, Palitzsch KD. Schäffler A, et al. J Clin Endocrinol Metab. 2000 Jun;85(6):2287-92. doi: 10.1210/jcem.85.6.6637. J Clin Endocrinol Metab. 2000. PMID: 10852465
Amelioration of hyperglycemic and hyperosmotic induced vascular dysfunction by in vivo inhibition of protein kinase C and p38 MAP kinase pathway in the rat mesenteric microcirculation.
Schäffler A, Arndt H, Schölmerich J, Palitzsch KD. Schäffler A, et al. Eur J Clin Invest. 2000 Jul;30(7):586-93. doi: 10.1046/j.1365-2362.2000.00680.x. Eur J Clin Invest. 2000. PMID: 10886298
Acutely induced hyperglycemia resulted in a significant increase in leukocyte emigration. This effect could be imitated by mannitol. ...The PKC/MAP kinase cascade is involved as a signal transducing component. The reduction of leukocyte rolling velocity is a …
Acutely induced hyperglycemia resulted in a significant increase in leukocyte emigration. This effect could be imitated by mannitol. …
207 results