Jacobs HT - Search Results

1

Replication of vertebrate mitochondrial DNA entails transient ribonucleotide incorporation throughout the lagging strand.

Yasukawa T, Reyes A, Cluett TJ, Yang MY, Bowmaker M, Jacobs HT, Holt IJ. Yasukawa T, et al. Among authors: jacobs ht. EMBO J. 2006 Nov 15;25(22):5358-71. doi: 10.1038/sj.emboj.7601392. Epub 2006 Oct 26. EMBO J. 2006. PMID: 17066082 Free PMC article.

2

Mitochondrial DNA replication proceeds via a 'bootlace' mechanism involving the incorporation of processed transcripts.

Reyes A, Kazak L, Wood SR, Yasukawa T, Jacobs HT, Holt IJ. Reyes A, et al. Among authors: jacobs ht. Nucleic Acids Res. 2013 Jun;41(11):5837-50. doi: 10.1093/nar/gkt196. Epub 2013 Apr 16. Nucleic Acids Res. 2013. PMID: 23595151 Free PMC article.

3

Unique features of DNA replication in mitochondria: a functional and evolutionary perspective.

Holt IJ, Jacobs HT. Holt IJ, et al. Among authors: jacobs ht. Bioessays. 2014 Nov;36(11):1024-31. doi: 10.1002/bies.201400052. Epub 2014 Sep 12. Bioessays. 2014. PMID: 25220172

4

Primer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication.

Holmes JB, Akman G, Wood SR, Sakhuja K, Cerritelli SM, Moss C, Bowmaker MR, Jacobs HT, Crouch RJ, Holt IJ. Holmes JB, et al. Among authors: jacobs ht. Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):9334-9. doi: 10.1073/pnas.1503653112. Epub 2015 Jul 10. Proc Natl Acad Sci U S A. 2015. PMID: 26162680 Free PMC article.

5

Mammalian mitochondrial DNA replicates bidirectionally from an initiation zone.

Bowmaker M, Yang MY, Yasukawa T, Reyes A, Jacobs HT, Huberman JA, Holt IJ. Bowmaker M, et al. Among authors: jacobs ht. J Biol Chem. 2003 Dec 19;278(51):50961-9. doi: 10.1074/jbc.M308028200. Epub 2003 Sep 23. J Biol Chem. 2003. PMID: 14506235 Free article.

6

A bidirectional origin of replication maps to the major noncoding region of human mitochondrial DNA.

Yasukawa T, Yang MY, Jacobs HT, Holt IJ. Yasukawa T, et al. Among authors: jacobs ht. Mol Cell. 2005 Jun 10;18(6):651-62. doi: 10.1016/j.molcel.2005.05.002. Mol Cell. 2005. PMID: 15949440 Free article.

7

Biased incorporation of ribonucleotides on the mitochondrial L-strand accounts for apparent strand-asymmetric DNA replication.

Yang MY, Bowmaker M, Reyes A, Vergani L, Angeli P, Gringeri E, Jacobs HT, Holt IJ. Yang MY, et al. Among authors: jacobs ht. Cell. 2002 Nov 15;111(4):495-505. doi: 10.1016/s0092-8674(02)01075-9. Cell. 2002. PMID: 12437923 Free article.

8

Coupled leading- and lagging-strand synthesis of mammalian mitochondrial DNA.

Holt IJ, Lorimer HE, Jacobs HT. Holt IJ, et al. Among authors: jacobs ht. Cell. 2000 Mar 3;100(5):515-24. doi: 10.1016/s0092-8674(00)80688-1. Cell. 2000. PMID: 10721989 Free article.

9

Prominent mitochondrial DNA recombination intermediates in human heart muscle.

Kajander OA, Karhunen PJ, Holt IJ, Jacobs HT. Kajander OA, et al. Among authors: jacobs ht. EMBO Rep. 2001 Nov;2(11):1007-12. doi: 10.1093/embo-reports/kve233. EMBO Rep. 2001. PMID: 11713192 Free PMC article.

10

The mitochondrial transcription termination factor mTERF modulates replication pausing in human mitochondrial DNA.

Hyvärinen AK, Pohjoismäki JL, Reyes A, Wanrooij S, Yasukawa T, Karhunen PJ, Spelbrink JN, Holt IJ, Jacobs HT. Hyvärinen AK, et al. Among authors: jacobs ht. Nucleic Acids Res. 2007;35(19):6458-74. doi: 10.1093/nar/gkm676. Epub 2007 Sep 20. Nucleic Acids Res. 2007. PMID: 17884915 Free PMC article.

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