Xu L - Search Results

1

Immune response after neonatal transfer of a human factor IX-expressing retroviral vector in dogs, cats, and mice.

Xu L, Mei M, Haskins ME, Nichols TC, O'donnell P, Cullen K, Dillow A, Bellinger D, Ponder KP. Xu L, et al. Thromb Res. 2007;120(2):269-80. doi: 10.1016/j.thromres.2006.09.010. Epub 2006 Nov 7. Thromb Res. 2007. PMID: 17095052

2

Transduction of hepatocytes after neonatal delivery of a Moloney murine leukemia virus based retroviral vector results in long-term expression of beta-glucuronidase in mucopolysaccharidosis VII dogs.

Xu L, Haskins ME, Melniczek JR, Gao C, Weil MA, O'Malley TM, O'Donnell PA, Mazrier H, Ellinwood NM, Zweigle J, Wolfe JH, Ponder KP. Xu L, et al. Mol Ther. 2002 Feb;5(2):141-53. doi: 10.1006/mthe.2002.0527. Mol Ther. 2002. PMID: 11829521 Free article.

3

Neonatal or hepatocyte growth factor-potentiated adult gene therapy with a retroviral vector results in therapeutic levels of canine factor IX for hemophilia B.

Xu L, Gao C, Sands MS, Cai SR, Nichols TC, Bellinger DA, Raymer RA, McCorquodale S, Ponder KP. Xu L, et al. Blood. 2003 May 15;101(10):3924-32. doi: 10.1182/blood-2002-10-3050. Epub 2003 Jan 16. Blood. 2003. PMID: 12531787 Free article.

4

Neonatal gene transfer with a retroviral vector results in tolerance to human factor IX in mice and dogs.

Zhang J, Xu L, Haskins ME, Parker Ponder K. Zhang J, et al. Among authors: xu l. Blood. 2004 Jan 1;103(1):143-51. doi: 10.1182/blood-2003-06-2181. Epub 2003 Sep 11. Blood. 2004. PMID: 12969967 Free article.

5

In vivo transduction of hematopoietic stem cells after neonatal intravenous injection of an amphotropic retroviral vector in mice.

Xu L, O'Malley T, Sands MS, Wang B, Meyerrose T, Haskins ME, Ponder KP. Xu L, et al. Mol Ther. 2004 Jul;10(1):37-44. doi: 10.1016/j.ymthe.2004.04.010. Mol Ther. 2004. PMID: 15233940 Free article.

6

Absence of a desmopressin response after therapeutic expression of factor VIII in hemophilia A dogs with liver-directed neonatal gene therapy.

Xu L, Nichols TC, Sarkar R, McCorquodale S, Bellinger DA, Ponder KP. Xu L, et al. Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6080-5. doi: 10.1073/pnas.0409249102. Epub 2005 Apr 18. Proc Natl Acad Sci U S A. 2005. PMID: 15837921 Free PMC article.

7

Expression in blood cells may contribute to biochemical and pathological improvements after neonatal intravenous gene therapy for mucopolysaccharidosis VII in dogs.

Wang B, O'Malley TM, Xu L, Vite C, Wang P, O'Donnell PA, Ellinwood NM, Haskins ME, Ponder KP. Wang B, et al. Among authors: xu l. Mol Genet Metab. 2006 Jan;87(1):8-21. doi: 10.1016/j.ymgme.2005.08.014. Epub 2005 Nov 7. Mol Genet Metab. 2006. PMID: 16275036

8

High expression reduces an antibody response after neonatal gene therapy with B domain-deleted human factor VIII in mice.

Xu L, Mei M, Ma X, Ponder KP. Xu L, et al. J Thromb Haemost. 2007 Sep;5(9):1805-12. doi: 10.1111/j.1538-7836.2007.02629.x. Epub 2007 May 21. J Thromb Haemost. 2007. PMID: 17596134 Free article.

9

Therapeutic neonatal hepatic gene therapy in mucopolysaccharidosis VII dogs.

Ponder KP, Melniczek JR, Xu L, Weil MA, O'Malley TM, O'Donnell PA, Knox VW, Aguirre GD, Mazrier H, Ellinwood NM, Sleeper M, Maguire AM, Volk SW, Mango RL, Zweigle J, Wolfe JH, Haskins ME. Ponder KP, et al. Among authors: xu l. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13102-7. doi: 10.1073/pnas.192353499. Epub 2002 Sep 13. Proc Natl Acad Sci U S A. 2002. PMID: 12232044 Free PMC article.

10

Evaluation of pathological manifestations of disease in mucopolysaccharidosis VII mice after neonatal hepatic gene therapy.

Xu L, Mango RL, Sands MS, Haskins ME, Ellinwood NM, Ponder KP. Xu L, et al. Mol Ther. 2002 Dec;6(6):745-58. doi: 10.1006/mthe.2002.0809. Mol Ther. 2002. PMID: 12498771 Free article.

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