Ratcliffe SJ - Search Results

1

Synthesis and characterization of 5'-p-fluorosulfonylbenzoyl-2' (or 3')-(biotinyl)adenosine as an activity-based probe for protein kinases.

Ratcliffe SJ, Yi T, Khandekar SS. Ratcliffe SJ, et al. J Biomol Screen. 2007 Feb;12(1):126-32. doi: 10.1177/1087057106296685. Epub 2006 Dec 8. J Biomol Screen. 2007. PMID: 17166825

2

A High-Throughput Screen to Identify LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease Using RapidFire Mass Spectrometry.

Leveridge M, Collier L, Edge C, Hardwicke P, Leavens B, Ratcliffe S, Rees M, Stasi LP, Nadin A, Reith AD. Leveridge M, et al. J Biomol Screen. 2016 Feb;21(2):145-55. doi: 10.1177/1087057115606707. Epub 2015 Sep 24. J Biomol Screen. 2016. PMID: 26403521

3

Demonstrating enhanced throughput of RapidFire mass spectrometry through multiplexing using the JmjD2d demethylase as a model system.

Leveridge M, Buxton R, Argyrou A, Francis P, Leavens B, West A, Rees M, Hardwicke P, Bridges A, Ratcliffe S, Chung CW. Leveridge M, et al. J Biomol Screen. 2014 Feb;19(2):278-86. doi: 10.1177/1087057113496276. Epub 2013 Jul 29. J Biomol Screen. 2014. PMID: 23896685

4

The quest for Factor VIIa exosite inhibitors.

Amour A, Hutchinson J, Ruiz Avendaño AM, Ratcliffe S, Alvarez E, Martin J, Toomey JR, Senger S, Wolfendale M, Mooney C. Amour A, et al. Biochem Soc Trans. 2007 Jun;35(Pt 3):555-8. doi: 10.1042/BST0350555. Biochem Soc Trans. 2007. PMID: 17511650

5

A broad-spectrum fluorescence-based peptide library for the rapid identification of protease substrates.

Thomas DA, Francis P, Smith C, Ratcliffe S, Ede NJ, Kay C, Wayne G, Martin SL, Moore K, Amour A, Hooper NM. Thomas DA, et al. Proteomics. 2006 Apr;6(7):2112-20. doi: 10.1002/pmic.200500153. Proteomics. 2006. PMID: 16479534

6

Development of a high throughput cell-based assay for soluble epoxide hydrolase using BacMam technology.

Xie W, Tang X, Lu Q, Ames RS, Ratcliffe SJ, Li H. Xie W, et al. Among authors: ratcliffe sj. Mol Biotechnol. 2010 Jul;45(3):207-17. doi: 10.1007/s12033-010-9271-8. Mol Biotechnol. 2010. PMID: 20339956

7

Coupling the core of the anticancer drug etoposide to an oligonucleotide induces topoisomerase II-mediated cleavage at specific DNA sequences.

Infante Lara L, Fenner S, Ratcliffe S, Isidro-Llobet A, Hann M, Bax B, Osheroff N. Infante Lara L, et al. Nucleic Acids Res. 2018 Mar 16;46(5):2218-2233. doi: 10.1093/nar/gky072. Nucleic Acids Res. 2018. PMID: 29447373 Free PMC article.

8

Bifunctional chelators for copper radiopharmaceuticals: the synthesis of [Cu(ATSM)-amino acid] and [Cu(ATSM)-octreotide] conjugates.

Cowley AR, Dilworth JR, Donnelly PS, Heslop JM, Ratcliffe SJ. Cowley AR, et al. Among authors: ratcliffe sj. Dalton Trans. 2007 Jan 14;(2):209-17. doi: 10.1039/b612142j. Epub 2006 Nov 14. Dalton Trans. 2007. PMID: 17180189

9

Kinematic signature of high risk labored breathing revealed by novel signal analysis.

Ashe WB, McNamara BD, Patel SM, Shanno JN, Innis SE, Hochheimer CJ, Barros AJ, Williams RD, Ratcliffe SJ, Moorman JR, Gadrey SM. Ashe WB, et al. Among authors: ratcliffe sj. Sci Rep. 2024 Nov 13;14(1):27794. doi: 10.1038/s41598-024-77778-9. Sci Rep. 2024. PMID: 39537659 Free PMC article.

10

Prospective validation of clinical deterioration predictive models prior to intensive care unit transfer among patients admitted to acute care cardiology wards.

Keim-Malpass J, Moorman LP, Moorman JR, Hamil S, Yousefvand G, Monfredi OJ, Ratcliffe SJ, Krahn KN, Jones MK, Clark MT, Bourque JM. Keim-Malpass J, et al. Among authors: ratcliffe sj. Physiol Meas. 2024 Jun 5;45(6). doi: 10.1088/1361-6579/ad4e90. Physiol Meas. 2024. PMID: 38772399 Clinical Trial.

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