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Page 1
Subdominant CD8+ T-cell responses are involved in durable control of AIDS virus replication.
Friedrich TC, Valentine LE, Yant LJ, Rakasz EG, Piaskowski SM, Furlott JR, Weisgrau KL, Burwitz B, May GE, León EJ, Soma T, Napoe G, Capuano SV 3rd, Wilson NA, Watkins DI. Friedrich TC, et al. Among authors: leon ej. J Virol. 2007 Apr;81(7):3465-76. doi: 10.1128/JVI.02392-06. Epub 2007 Jan 24. J Virol. 2007. PMID: 17251286 Free PMC article.
CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation.
Loffredo JT, Friedrich TC, León EJ, Stephany JJ, Rodrigues DS, Spencer SP, Bean AT, Beal DR, Burwitz BJ, Rudersdorf RA, Wallace LT, Piaskowski SM, May GE, Sidney J, Gostick E, Wilson NA, Price DA, Kallas EG, Piontkivska H, Hughes AL, Sette A, Watkins DI. Loffredo JT, et al. Among authors: leon ej. PLoS One. 2007 Nov 14;2(11):e1152. doi: 10.1371/journal.pone.0001152. PLoS One. 2007. PMID: 18000532 Free PMC article.
Patterns of CD8+ immunodominance may influence the ability of Mamu-B*08-positive macaques to naturally control simian immunodeficiency virus SIVmac239 replication.
Loffredo JT, Bean AT, Beal DR, León EJ, May GE, Piaskowski SM, Furlott JR, Reed J, Musani SK, Rakasz EG, Friedrich TC, Wilson NA, Allison DB, Watkins DI. Loffredo JT, et al. Among authors: leon ej. J Virol. 2008 Feb;82(4):1723-38. doi: 10.1128/JVI.02084-07. Epub 2007 Dec 5. J Virol. 2008. PMID: 18057253 Free PMC article.
Comprehensive immunological evaluation reveals surprisingly few differences between elite controller and progressor Mamu-B*17-positive simian immunodeficiency virus-infected rhesus macaques.
Maness NJ, Yant LJ, Chung C, Loffredo JT, Friedrich TC, Piaskowski SM, Furlott J, May GE, Soma T, León EJ, Wilson NA, Piontkivska H, Hughes AL, Sidney J, Sette A, Watkins DI. Maness NJ, et al. Among authors: leon ej. J Virol. 2008 Jun;82(11):5245-54. doi: 10.1128/JVI.00292-08. Epub 2008 Apr 2. J Virol. 2008. PMID: 18385251 Free PMC article.
Macaques vaccinated with live-attenuated SIV control replication of heterologous virus.
Reynolds MR, Weiler AM, Weisgrau KL, Piaskowski SM, Furlott JR, Weinfurter JT, Kaizu M, Soma T, León EJ, MacNair C, Leaman DP, Zwick MB, Gostick E, Musani SK, Price DA, Friedrich TC, Rakasz EG, Wilson NA, McDermott AB, Boyle R, Allison DB, Burton DR, Koff WC, Watkins DI. Reynolds MR, et al. Among authors: leon ej. J Exp Med. 2008 Oct 27;205(11):2537-50. doi: 10.1084/jem.20081524. Epub 2008 Oct 6. J Exp Med. 2008. PMID: 18838548 Free PMC article.
Gag- and Nef-specific CD4+ T cells recognize and inhibit SIV replication in infected macrophages early after infection.
Sacha JB, Giraldo-Vela JP, Buechler MB, Martins MA, Maness NJ, Chung C, Wallace LT, León EJ, Friedrich TC, Wilson NA, Hiraoka A, Watkins DI. Sacha JB, et al. Among authors: leon ej. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9791-6. doi: 10.1073/pnas.0813106106. Epub 2009 May 28. Proc Natl Acad Sci U S A. 2009. PMID: 19478057 Free PMC article.
Infection with "escaped" virus variants impairs control of simian immunodeficiency virus SIVmac239 replication in Mamu-B*08-positive macaques.
Valentine LE, Loffredo JT, Bean AT, León EJ, MacNair CE, Beal DR, Piaskowski SM, Klimentidis YC, Lank SM, Wiseman RW, Weinfurter JT, May GE, Rakasz EG, Wilson NA, Friedrich TC, O'Connor DH, Allison DB, Watkins DI. Valentine LE, et al. Among authors: leon ej. J Virol. 2009 Nov;83(22):11514-27. doi: 10.1128/JVI.01298-09. Epub 2009 Sep 2. J Virol. 2009. PMID: 19726517 Free PMC article.
High viremia is associated with high levels of in vivo major histocompatibility complex class I Downregulation in rhesus macaques infected with simian immunodeficiency virus SIVmac239.
Friedrich TC, Piaskowski SM, León EJ, Furlott JR, Maness NJ, Weisgrau KL, Mac Nair CE, Weiler AM, Loffredo JT, Reynolds MR, Williams KY, Klimentidis YC, Wilson NA, Allison DB, Rakasz EG. Friedrich TC, et al. Among authors: leon ej. J Virol. 2010 May;84(10):5443-7. doi: 10.1128/JVI.02452-09. Epub 2010 Mar 10. J Virol. 2010. PMID: 20219903 Free PMC article.
Macaques vaccinated with simian immunodeficiency virus SIVmac239Delta nef delay acquisition and control replication after repeated low-dose heterologous SIV challenge.
Reynolds MR, Weiler AM, Piaskowski SM, Kolar HL, Hessell AJ, Weiker M, Weisgrau KL, León EJ, Rogers WE, Makowsky R, McDermott AB, Boyle R, Wilson NA, Allison DB, Burton DR, Koff WC, Watkins DI. Reynolds MR, et al. Among authors: leon ej. J Virol. 2010 Sep;84(18):9190-9. doi: 10.1128/JVI.00041-10. Epub 2010 Jun 30. J Virol. 2010. PMID: 20592091 Free PMC article.
Macaque long-term nonprogressors resist superinfection with multiple CD8+ T cell escape variants of simian immunodeficiency virus.
Weinfurter JT, May GE, Soma T, Hessell AJ, León EJ, Macnair CE, Piaskowski SM, Weisgrau K, Furlott J, Maness NJ, Reed J, Wilson NA, Rakasz EG, Burton DR, Friedrich TC. Weinfurter JT, et al. Among authors: leon ej. J Virol. 2011 Jan;85(1):530-41. doi: 10.1128/JVI.01025-10. Epub 2010 Oct 20. J Virol. 2011. PMID: 20962091 Free PMC article.
34 results