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Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria.
Wirawan E, Vande Walle L, Kersse K, Cornelis S, Claerhout S, Vanoverberghe I, Roelandt R, De Rycke R, Verspurten J, Declercq W, Agostinis P, Vanden Berghe T, Lippens S, Vandenabeele P. Wirawan E, et al. Among authors: cornelis s. Cell Death Dis. 2010;1(1):e18. doi: 10.1038/cddis.2009.16. Cell Death Dis. 2010. PMID: 21364619 Free PMC article.
Inflammatory caspases: targets for novel therapies.
Cornelis S, Kersse K, Festjens N, Lamkanfi M, Vandenabeele P. Cornelis S, et al. Curr Pharm Des. 2007;13(4):367-85. doi: 10.2174/138161207780163006. Curr Pharm Des. 2007. PMID: 17311555 Review.
TNF-induced intracellular signaling leading to gene induction or to cytotoxicity by necrosis or by apoptosis.
Fiers W, Beyaert R, Boone E, Cornelis S, Declercq W, Decoster E, Denecker G, Depuydt B, De Valck D, De Wilde G, Goossens V, Grooten J, Haegeman G, Heyninck K, Penning L, Plaisance S, Vancompernolle K, Van Criekinge W, Vandenabeele P, Vanden Berghe W, Van de Craen M, Vandevoorde V, Vercammen D. Fiers W, et al. Among authors: cornelis s. J Inflamm. 1995-1996;47(1-2):67-75. J Inflamm. 1995. PMID: 8913931 Review.
LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF-kappaB activation.
Wullaert A, Verstrepen L, Van Huffel S, Adib-Conquy M, Cornelis S, Kreike M, Haegman M, El Bakkouri K, Sanders M, Verhelst K, Carpentier I, Cavaillon JM, Heyninck K, Beyaert R. Wullaert A, et al. Among authors: cornelis s. J Biol Chem. 2007 Jan 5;282(1):81-90. doi: 10.1074/jbc.M607481200. Epub 2006 Nov 6. J Biol Chem. 2007. PMID: 17088249 Free article.
85 results