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Regulation of androgen receptor-mediated transcription by RPB5 binding protein URI/RMP.
Mita P, Savas JN, Djouder N, Yates JR 3rd, Ha S, Ruoff R, Schafler ED, Nwachukwu JC, Tanese N, Cowan NJ, Zavadil J, Garabedian MJ, Logan SK. Mita P, et al. Among authors: nwachukwu jc. Mol Cell Biol. 2011 Sep;31(17):3639-52. doi: 10.1128/MCB.05429-11. Epub 2011 Jul 5. Mol Cell Biol. 2011. PMID: 21730289 Free PMC article.
Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells.
Stender JD, Nwachukwu JC, Kastrati I, Kim Y, Strid T, Yakir M, Srinivasan S, Nowak J, Izard T, Rangarajan ES, Carlson KE, Katzenellenbogen JA, Yao XQ, Grant BJ, Leong HS, Lin CY, Frasor J, Nettles KW, Glass CK. Stender JD, et al. Among authors: nwachukwu jc. Mol Cell. 2017 Mar 16;65(6):1122-1135.e5. doi: 10.1016/j.molcel.2017.02.008. Mol Cell. 2017. PMID: 28306507 Free PMC article.
First-trimester trophoblast cell model gene response to hypoxia.
Koklanaris N, Nwachukwu JC, Huang SJ, Guller S, Karpisheva K, Garabedian M, Lee MJ. Koklanaris N, et al. Among authors: nwachukwu jc. Am J Obstet Gynecol. 2006 Mar;194(3):687-93. doi: 10.1016/j.ajog.2006.01.067. Am J Obstet Gynecol. 2006. PMID: 16522398
The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells.
Fanning SW, Jeselsohn R, Dharmarajan V, Mayne CG, Karimi M, Buchwalter G, Houtman R, Toy W, Fowler CE, Han R, Lainé M, Carlson KE, Martin TA, Nowak J, Nwachukwu JC, Hosfield DJ, Chandarlapaty S, Tajkhorshid E, Nettles KW, Griffin PR, Shen Y, Katzenellenbogen JA, Brown M, Greene GL. Fanning SW, et al. Among authors: nwachukwu jc. Elife. 2018 Nov 29;7:e37161. doi: 10.7554/eLife.37161. Elife. 2018. PMID: 30489256 Free PMC article.
Systems Structural Biology Analysis of Ligand Effects on ERα Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Nwachukwu JC, Srinivasan S, Bruno NE, Nowak J, Wright NJ, Minutolo F, Rangarajan ES, Izard T, Yao XQ, Grant BJ, Kojetin DJ, Elemento O, Katzenellenbogen JA, Nettles KW. Nwachukwu JC, et al. Cell Chem Biol. 2017 Jan 19;24(1):35-45. doi: 10.1016/j.chembiol.2016.11.014. Epub 2016 Dec 29. Cell Chem Biol. 2017. PMID: 28042045 Free article.
Predictive features of ligand-specific signaling through the estrogen receptor.
Nwachukwu JC, Srinivasan S, Zheng Y, Wang S, Min J, Dong C, Liao Z, Nowak J, Wright NJ, Houtman R, Carlson KE, Josan JS, Elemento O, Katzenellenbogen JA, Zhou HB, Nettles KW. Nwachukwu JC, et al. Mol Syst Biol. 2016 Apr 22;12(4):864. doi: 10.15252/msb.20156701. Mol Syst Biol. 2016. PMID: 27107013 Free PMC article.
Structural mechanism for signal transduction in RXR nuclear receptor heterodimers.
Kojetin DJ, Matta-Camacho E, Hughes TS, Srinivasan S, Nwachukwu JC, Cavett V, Nowak J, Chalmers MJ, Marciano DP, Kamenecka TM, Shulman AI, Rance M, Griffin PR, Bruning JB, Nettles KW. Kojetin DJ, et al. Among authors: nwachukwu jc. Nat Commun. 2015 Aug 20;6:8013. doi: 10.1038/ncomms9013. Nat Commun. 2015. PMID: 26289479 Free PMC article.
41 results