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ASPP proteins specifically stimulate the apoptotic function of p53.
Samuels-Lev Y, O'Connor DJ, Bergamaschi D, Trigiante G, Hsieh JK, Zhong S, Campargue I, Naumovski L, Crook T, Lu X. Samuels-Lev Y, et al. Among authors: lu x. Mol Cell. 2001 Oct;8(4):781-94. doi: 10.1016/s1097-2765(01)00367-7. Mol Cell. 2001. PMID: 11684014 Free article.
iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.
Bergamaschi D, Samuels Y, O'Neil NJ, Trigiante G, Crook T, Hsieh JK, O'Connor DJ, Zhong S, Campargue I, Tomlinson ML, Kuwabara PE, Lu X. Bergamaschi D, et al. Among authors: lu x. Nat Genet. 2003 Feb;33(2):162-7. doi: 10.1038/ng1070. Epub 2003 Jan 13. Nat Genet. 2003. PMID: 12524540
p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis.
Bergamaschi D, Gasco M, Hiller L, Sullivan A, Syed N, Trigiante G, Yulug I, Merlano M, Numico G, Comino A, Attard M, Reelfs O, Gusterson B, Bell AK, Heath V, Tavassoli M, Farrell PJ, Smith P, Lu X, Crook T. Bergamaschi D, et al. Among authors: lu x. Cancer Cell. 2003 Apr;3(4):387-402. doi: 10.1016/s1535-6108(03)00079-5. Cancer Cell. 2003. PMID: 12726864 Free article.
ASPP1 and ASPP2: common activators of p53 family members.
Bergamaschi D, Samuels Y, Jin B, Duraisingham S, Crook T, Lu X. Bergamaschi D, et al. Among authors: lu x. Mol Cell Biol. 2004 Feb;24(3):1341-50. doi: 10.1128/MCB.24.3.1341-1350.2004. Mol Cell Biol. 2004. PMID: 14729977 Free PMC article.
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