Ilkayeva OR - Search Results

1

Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis.

Zhang YM, Chohnan S, Virga KG, Stevens RD, Ilkayeva OR, Wenner BR, Bain JR, Newgard CB, Lee RE, Rock CO, Jackowski S. Zhang YM, et al. Among authors: ilkayeva or. Chem Biol. 2007 Mar;14(3):291-302. doi: 10.1016/j.chembiol.2007.01.013. Chem Biol. 2007. PMID: 17379144 Free PMC article.

2

Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency.

Koves TR, Li P, An J, Akimoto T, Slentz D, Ilkayeva O, Dohm GL, Yan Z, Newgard CB, Muoio DM. Koves TR, et al. J Biol Chem. 2005 Sep 30;280(39):33588-98. doi: 10.1074/jbc.M507621200. Epub 2005 Aug 3. J Biol Chem. 2005. PMID: 16079133 Free article.

3

Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion.

Jensen MV, Joseph JW, Ilkayeva O, Burgess S, Lu D, Ronnebaum SM, Odegaard M, Becker TC, Sherry AD, Newgard CB. Jensen MV, et al. J Biol Chem. 2006 Aug 4;281(31):22342-22351. doi: 10.1074/jbc.M604350200. Epub 2006 Jun 1. J Biol Chem. 2006. PMID: 16740637 Free article.

4

A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase regulates glucose-stimulated insulin secretion.

Ronnebaum SM, Ilkayeva O, Burgess SC, Joseph JW, Lu D, Stevens RD, Becker TC, Sherry AD, Newgard CB, Jensen MV. Ronnebaum SM, et al. J Biol Chem. 2006 Oct 13;281(41):30593-602. doi: 10.1074/jbc.M511908200. Epub 2006 Aug 15. J Biol Chem. 2006. PMID: 16912049 Free article.

5

The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion.

Joseph JW, Jensen MV, Ilkayeva O, Palmieri F, Alárcon C, Rhodes CJ, Newgard CB. Joseph JW, et al. J Biol Chem. 2006 Nov 24;281(47):35624-32. doi: 10.1074/jbc.M602606200. Epub 2006 Sep 25. J Biol Chem. 2006. PMID: 17001083 Free article.

6

Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance.

Koves TR, Ussher JR, Noland RC, Slentz D, Mosedale M, Ilkayeva O, Bain J, Stevens R, Dyck JR, Newgard CB, Lopaschuk GD, Muoio DM. Koves TR, et al. Cell Metab. 2008 Jan;7(1):45-56. doi: 10.1016/j.cmet.2007.10.013. Cell Metab. 2008. PMID: 18177724 Free article.

7

Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling.

Ferrara CT, Wang P, Neto EC, Stevens RD, Bain JR, Wenner BR, Ilkayeva OR, Keller MP, Blasiole DA, Kendziorski C, Yandell BS, Newgard CB, Attie AD. Ferrara CT, et al. Among authors: ilkayeva or. PLoS Genet. 2008 Mar 14;4(3):e1000034. doi: 10.1371/journal.pgen.1000034. PLoS Genet. 2008. PMID: 18369453 Free PMC article.

8

Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism.

Ronnebaum SM, Joseph JW, Ilkayeva O, Burgess SC, Lu D, Becker TC, Sherry AD, Newgard CB. Ronnebaum SM, et al. J Biol Chem. 2008 May 23;283(21):14248-56. doi: 10.1074/jbc.M800119200. Epub 2008 Apr 1. J Biol Chem. 2008. PMID: 18381287 Free PMC article.

9

Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent islets.

Ronnebaum SM, Jensen MV, Hohmeier HE, Burgess SC, Zhou YP, Qian S, MacNeil D, Howard A, Thornberry N, Ilkayeva O, Lu D, Sherry AD, Newgard CB. Ronnebaum SM, et al. J Biol Chem. 2008 Oct 24;283(43):28909-17. doi: 10.1074/jbc.M804665200. Epub 2008 Aug 28. J Biol Chem. 2008. PMID: 18755687 Free PMC article.

10

Metabolic profiling of PPARalpha-/- mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation.

Makowski L, Noland RC, Koves TR, Xing W, Ilkayeva OR, Muehlbauer MJ, Stevens RD, Muoio DM. Makowski L, et al. Among authors: ilkayeva or. FASEB J. 2009 Feb;23(2):586-604. doi: 10.1096/fj.08-119420. Epub 2008 Oct 22. FASEB J. 2009. PMID: 18945875 Free PMC article.

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