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The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.
Dissanayake SK, Wade M, Johnson CE, O'Connell MP, Leotlela PD, French AD, Shah KV, Hewitt KJ, Rosenthal DT, Indig FE, Jiang Y, Nickoloff BJ, Taub DD, Trent JM, Moon RT, Bittner M, Weeraratna AT. Dissanayake SK, et al. Among authors: french ad. J Biol Chem. 2007 Jun 8;282(23):17259-71. doi: 10.1074/jbc.M700075200. Epub 2007 Apr 10. J Biol Chem. 2007. PMID: 17426020 Free PMC article.
Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation.
Dissanayake SK, Olkhanud PB, O'Connell MP, Carter A, French AD, Camilli TC, Emeche CD, Hewitt KJ, Rosenthal DT, Leotlela PD, Wade MS, Yang SW, Brant L, Nickoloff BJ, Messina JL, Biragyn A, Hoek KS, Taub DD, Longo DL, Sondak VK, Hewitt SM, Weeraratna AT. Dissanayake SK, et al. Among authors: french ad. Cancer Res. 2008 Dec 15;68(24):10205-14. doi: 10.1158/0008-5472.CAN-08-2149. Cancer Res. 2008. PMID: 19074888 Free PMC article.
Assaying Wnt5A-mediated invasion in melanoma cells.
O'Connell MP, French AD, Leotlela PD, Weeraratna AT. O'Connell MP, et al. Among authors: french ad. Methods Mol Biol. 2008;468:243-53. doi: 10.1007/978-1-59745-249-6_19. Methods Mol Biol. 2008. PMID: 19099260 Free PMC article.
Wnt5A activates the calpain-mediated cleavage of filamin A.
O'Connell MP, Fiori JL, Baugher KM, Indig FE, French AD, Camilli TC, Frank BP, Earley R, Hoek KS, Hasskamp JH, Elias EG, Taub DD, Bernier M, Weeraratna AT. O'Connell MP, et al. Among authors: french ad. J Invest Dermatol. 2009 Jul;129(7):1782-9. doi: 10.1038/jid.2008.433. Epub 2009 Jan 29. J Invest Dermatol. 2009. PMID: 19177143 Free PMC article.
95 results