Douglas KT - Search Results

1

Design, synthesis and enzymatic evaluation of 6-bridged imidazolyluracil derivatives as inhibitors of human thymidine phosphorylase.

McNally VA, Rajabi M, Gbaj A, Stratford IJ, Edwards PN, Douglas KT, Bryce RA, Jaffar M, Freeman S. McNally VA, et al. Among authors: douglas kt. J Pharm Pharmacol. 2007 Apr;59(4):537-47. doi: 10.1211/jpp.59.4.0008. J Pharm Pharmacol. 2007. PMID: 17430637

2

Potential tumor-selective nitroimidazolylmethyluracil prodrug derivatives: inhibitors of the angiogenic enzyme thymidine phosphorylase.

Cole C, Reigan P, Gbaj A, Edwards PN, Douglas KT, Stratford IJ, Freeman S, Jaffar M. Cole C, et al. Among authors: douglas kt. J Med Chem. 2003 Jan 16;46(2):207-9. doi: 10.1021/jm020964w. J Med Chem. 2003. PMID: 12519058

3

Synthesis and enzymatic evaluation of xanthine oxidase-activated prodrugs based on inhibitors of thymidine phosphorylase.

Reigan P, Gbaj A, Chinje E, Stratford IJ, Douglas KT, Freeman S. Reigan P, et al. Among authors: douglas kt. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5247-50. doi: 10.1016/j.bmcl.2004.08.036. Bioorg Med Chem Lett. 2004. PMID: 15454205

4

Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.

Reigan P, Edwards PN, Gbaj A, Cole C, Barry ST, Page KM, Ashton SE, Luke RW, Douglas KT, Stratford IJ, Jaffar M, Bryce RA, Freeman S. Reigan P, et al. Among authors: douglas kt. J Med Chem. 2005 Jan 27;48(2):392-402. doi: 10.1021/jm049494r. J Med Chem. 2005. PMID: 15658853

5

Thymidine phosphorylase from Escherichia coli: tight-binding inhibitors as enzyme active-site titrants.

Gbaj A, Edwards PN, Reigan P, Freeman S, Jaffar M, Douglas KT. Gbaj A, et al. Among authors: douglas kt. J Enzyme Inhib Med Chem. 2006 Feb;21(1):69-73. doi: 10.1080/14756360500424010. J Enzyme Inhib Med Chem. 2006. PMID: 16570508 Free article.

6

Cole C, Marks DS, Jaffar M, Stratford IJ, Douglas KT, Freeman S. Cole C, et al. Among authors: douglas kt. Anticancer Drug Des. 1999 Oct;14(5):411-20. Anticancer Drug Des. 1999. PMID: 10766296

7

Identification of a novel class of inhibitor of human and Escherichia coli thymidine phosphorylase by in silico screening.

McNally VA, Gbaj A, Douglas KT, Stratford IJ, Jaffar M, Freeman S, Bryce RA. McNally VA, et al. Among authors: douglas kt. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3705-9. doi: 10.1016/j.bmcl.2003.08.010. Bioorg Med Chem Lett. 2003. PMID: 14552762

8

Benzoic acid and pyridine derivatives as inhibitors of Trypanosoma cruzi trans-sialidase.

Neres J, Bonnet P, Edwards PN, Kotian PL, Buschiazzo A, Alzari PM, Bryce RA, Douglas KT. Neres J, et al. Among authors: douglas kt. Bioorg Med Chem. 2007 Mar 1;15(5):2106-19. doi: 10.1016/j.bmc.2006.12.024. Epub 2006 Dec 15. Bioorg Med Chem. 2007. PMID: 17218104

9

Discovery of novel inhibitors of Trypanosoma cruzi trans-sialidase from in silico screening.

Neres J, Brewer ML, Ratier L, Botti H, Buschiazzo A, Edwards PN, Mortenson PN, Charlton MH, Alzari PM, Frasch AC, Bryce RA, Douglas KT. Neres J, et al. Among authors: douglas kt. Bioorg Med Chem Lett. 2009 Feb 1;19(3):589-96. doi: 10.1016/j.bmcl.2008.12.065. Epub 2008 Dec 24. Bioorg Med Chem Lett. 2009. PMID: 19144516

10

Molecular probes: insights into design and analysis from computational and physical chemistry.

Mitchell FL, Marks GE, Bichenkova EV, Douglas KT, Bryce RA. Mitchell FL, et al. Among authors: douglas kt. Biochem Soc Trans. 2008 Feb;36(Pt 1):46-50. doi: 10.1042/BST0360046. Biochem Soc Trans. 2008. PMID: 18208383 Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

147 results

Search Page

Filters