Hughes PD - Search Results

1

ER stress triggers apoptosis by activating BH3-only protein Bim.

Puthalakath H, O'Reilly LA, Gunn P, Lee L, Kelly PN, Huntington ND, Hughes PD, Michalak EM, McKimm-Breschkin J, Motoyama N, Gotoh T, Akira S, Bouillet P, Strasser A. Puthalakath H, et al. Among authors: hughes pd. Cell. 2007 Jun 29;129(7):1337-49. doi: 10.1016/j.cell.2007.04.027. Cell. 2007. PMID: 17604722 Free article.

2

The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins.

Mérino D, Giam M, Hughes PD, Siggs OM, Heger K, O'Reilly LA, Adams JM, Strasser A, Lee EF, Fairlie WD, Bouillet P. Mérino D, et al. Among authors: hughes pd. J Cell Biol. 2009 Aug 10;186(3):355-62. doi: 10.1083/jcb.200905153. Epub 2009 Aug 3. J Cell Biol. 2009. PMID: 19651893 Free PMC article.

3

Role of Bim and other Bcl-2 family members in autoimmune and degenerative diseases.

Hughes P, Bouillet P, Strasser A. Hughes P, et al. Curr Dir Autoimmun. 2006;9:74-94. doi: 10.1159/000090773. Curr Dir Autoimmun. 2006. PMID: 16394656 Review.

4

Loss of PKD1 and loss of Bcl-2 elicit polycystic kidney disease through distinct mechanisms.

Hughes P, Robati M, Lu W, Zhou J, Strasser A, Bouillet P. Hughes P, et al. Cell Death Differ. 2006 Jul;13(7):1123-7. doi: 10.1038/sj.cdd.4401815. Epub 2005 Nov 11. Cell Death Differ. 2006. PMID: 16282979 Free PMC article.

5

Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity.

Hughes PD, Belz GT, Fortner KA, Budd RC, Strasser A, Bouillet P. Hughes PD, et al. Immunity. 2008 Feb;28(2):197-205. doi: 10.1016/j.immuni.2007.12.017. Immunity. 2008. PMID: 18275830 Free PMC article.

6

Overexpression of Mcl-1 exacerbates lymphocyte accumulation and autoimmune kidney disease in lpr mice.

Anstee NS, Vandenberg CJ, Campbell KJ, Hughes PD, O'Reilly LA, Cory S. Anstee NS, et al. Among authors: hughes pd. Cell Death Differ. 2017 Mar;24(3):397-408. doi: 10.1038/cdd.2016.125. Epub 2016 Nov 4. Cell Death Differ. 2017. PMID: 27813531 Free PMC article.

7

Loss of c-REL but not NF-κB2 prevents autoimmune disease driven by FasL mutation.

O'Reilly LA, Hughes P, Lin A, Waring P, Siebenlist U, Jain R, Gray DH, Gerondakis S, Strasser A. O'Reilly LA, et al. Cell Death Differ. 2015 May;22(5):767-78. doi: 10.1038/cdd.2014.168. Epub 2014 Oct 31. Cell Death Differ. 2015. PMID: 25361085 Free PMC article.

8

Impact of loss of NF-κB1, NF-κB2 or c-REL on SLE-like autoimmune disease and lymphadenopathy in Fas(lpr/lpr) mutant mice.

Low JT, Hughes P, Lin A, Siebenlist U, Jain R, Yaprianto K, Gray DH, Gerondakis S, Strasser A, O'Reilly LA. Low JT, et al. Immunol Cell Biol. 2016 Jan;94(1):66-78. doi: 10.1038/icb.2015.66. Epub 2015 Jun 18. Immunol Cell Biol. 2016. PMID: 26084385

9

Histological and Extended Clinical Outcomes After ABO-Incompatible Renal Transplantation Without Splenectomy or Rituximab.

Chow KV, Flint SM, Shen A, Landgren A, Finlay M, Murugasu A, Masterson R, Hughes P, Cohney SJ. Chow KV, et al. Transplantation. 2017 Jun;101(6):1433-1440. doi: 10.1097/TP.0000000000001415. Transplantation. 2017. PMID: 27495772

10

Suspected urinary leak in a renal transplant patient with unusual collecting system anatomy.

Hughes PD, Westcott JD, Gibson R, Francis DM, Becker GJ, Cohney SJ, Better N. Hughes PD, et al. Clin Nucl Med. 2004 Sep;29(9):592-4. doi: 10.1097/01.rlu.0000134999.91021.7a. Clin Nucl Med. 2004. PMID: 15311137 No abstract available.

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