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ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation.
Yang JY, Zong CS, Xia W, Yamaguchi H, Ding Q, Xie X, Lang JY, Lai CC, Chang CJ, Huang WC, Huang H, Kuo HP, Lee DF, Li LY, Lien HC, Cheng X, Chang KJ, Hsiao CD, Tsai FJ, Tsai CH, Sahin AA, Muller WJ, Mills GB, Yu D, Hortobagyi GN, Hung MC. Yang JY, et al. Among authors: xie x. Nat Cell Biol. 2008 Feb;10(2):138-48. doi: 10.1038/ncb1676. Epub 2008 Jan 20. Nat Cell Biol. 2008. PMID: 18204439 Free PMC article.
A novel hTERT promoter-driven E1A therapeutic for ovarian cancer.
Xie X, Hsu JL, Choi MG, Xia W, Yamaguchi H, Chen CT, Trinh BQ, Lu Z, Ueno NT, Wolf JK, Bast RC Jr, Hung MC. Xie X, et al. Mol Cancer Ther. 2009 Aug;8(8):2375-82. doi: 10.1158/1535-7163.MCT-09-0056. Epub 2009 Aug 11. Mol Cancer Ther. 2009. PMID: 19671744 Free PMC article.
ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway.
Kuo HP, Lee DF, Chen CT, Liu M, Chou CK, Lee HJ, Du Y, Xie X, Wei Y, Xia W, Weihua Z, Yang JY, Yen CJ, Huang TH, Tan M, Xing G, Zhao Y, Lin CH, Tsai SF, Fidler IJ, Hung MC. Kuo HP, et al. Among authors: xie x. Sci Signal. 2010 Feb 9;3(108):ra9. doi: 10.1126/scisignal.2000590. Sci Signal. 2010. PMID: 20145209 Free PMC article.
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