Luo X - Search Results

1

A three-helix homo-oligomerization domain containing BH3 and BH1 is responsible for the apoptotic activity of Bax.

George NM, Evans JJ, Luo X. George NM, et al. Among authors: luo x. Genes Dev. 2007 Aug 1;21(15):1937-48. doi: 10.1101/gad.1553607. Genes Dev. 2007. PMID: 17671092 Free PMC article.

2

Bax contains two functional mitochondrial targeting sequences and translocates to mitochondria in a conformational change- and homo-oligomerization-driven process.

George NM, Targy N, Evans JJ, Zhang L, Luo X. George NM, et al. Among authors: luo x. J Biol Chem. 2010 Jan 8;285(2):1384-92. doi: 10.1074/jbc.M109.049924. Epub 2009 Oct 30. J Biol Chem. 2010. PMID: 19880508 Free PMC article.

3

Perturbation of the Bcl-2 network and an induced Noxa/Bcl-xL interaction trigger mitochondrial dysfunction after DNA damage.

Lopez H, Zhang L, George NM, Liu X, Pang X, Evans JJD, Targy NM, Luo X. Lopez H, et al. Among authors: luo x. J Biol Chem. 2010 May 14;285(20):15016-15026. doi: 10.1074/jbc.M109.086231. Epub 2010 Mar 11. J Biol Chem. 2010. PMID: 20223826 Free PMC article.

4

Bcl-2 family interaction with the mitochondrial morphogenesis machinery.

Cleland MM, Norris KL, Karbowski M, Wang C, Suen DF, Jiao S, George NM, Luo X, Li Z, Youle RJ. Cleland MM, et al. Among authors: luo x. Cell Death Differ. 2011 Feb;18(2):235-47. doi: 10.1038/cdd.2010.89. Epub 2010 Jul 30. Cell Death Differ. 2011. PMID: 20671748 Free PMC article.

5

Selective involvement of BH3-only proteins and differential targets of Noxa in diverse apoptotic pathways.

Zhang L, Lopez H, George NM, Liu X, Pang X, Luo X. Zhang L, et al. Among authors: luo x. Cell Death Differ. 2011 May;18(5):864-73. doi: 10.1038/cdd.2010.152. Epub 2010 Nov 26. Cell Death Differ. 2011. PMID: 21113147 Free PMC article.

6

Active Bax and Bak are functional holins.

Pang X, Moussa SH, Targy NM, Bose JL, George NM, Gries C, Lopez H, Zhang L, Bayles KW, Young R, Luo X. Pang X, et al. Among authors: luo x. Genes Dev. 2011 Nov 1;25(21):2278-90. doi: 10.1101/gad.171645.111. Epub 2011 Oct 17. Genes Dev. 2011. PMID: 22006182 Free PMC article.

7

The carboxyl-terminal tail of Noxa protein regulates the stability of Noxa and Mcl-1.

Pang X, Zhang J, Lopez H, Wang Y, Li W, O'Neill KL, Evans JJ, George NM, Long J, Chen Y, Luo X. Pang X, et al. Among authors: luo x. J Biol Chem. 2014 Jun 20;289(25):17802-11. doi: 10.1074/jbc.M114.548172. Epub 2014 May 8. J Biol Chem. 2014. PMID: 24811167 Free PMC article.

8

Cleavage by Caspase 8 and Mitochondrial Membrane Association Activate the BH3-only Protein Bid during TRAIL-induced Apoptosis.

Huang K, Zhang J, O'Neill KL, Gurumurthy CB, Quadros RM, Tu Y, Luo X. Huang K, et al. Among authors: luo x. J Biol Chem. 2016 May 27;291(22):11843-51. doi: 10.1074/jbc.M115.711051. Epub 2016 Apr 6. J Biol Chem. 2016. PMID: 27053107 Free PMC article.

9

Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane.

O'Neill KL, Huang K, Zhang J, Chen Y, Luo X. O'Neill KL, et al. Among authors: luo x. Genes Dev. 2016 Apr 15;30(8):973-88. doi: 10.1101/gad.276725.115. Epub 2016 Apr 7. Genes Dev. 2016. PMID: 27056669 Free PMC article.

10

Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.

Zhang J, Huang K, O'Neill KL, Pang X, Luo X. Zhang J, et al. Among authors: luo x. Cell Death Dis. 2016 Jun 16;7(6):e2266. doi: 10.1038/cddis.2016.167. Cell Death Dis. 2016. PMID: 27310874 Free PMC article.

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