Egli M - Search Results

1

Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme.

Li F, Pallan PS, Maier MA, Rajeev KG, Mathieu SL, Kreutz C, Fan Y, Sanghvi J, Micura R, Rozners E, Manoharan M, Egli M. Li F, et al. Among authors: egli m. Nucleic Acids Res. 2007;35(19):6424-38. doi: 10.1093/nar/gkm664. Epub 2007 Sep 18. Nucleic Acids Res. 2007. PMID: 17881374 Free PMC article.

2

Crystal structure and improved antisense properties of 2'-O-(2-methoxyethyl)-RNA.

Teplova M, Minasov G, Tereshko V, Inamati GB, Cook PD, Manoharan M, Egli M. Teplova M, et al. Among authors: egli m. Nat Struct Biol. 1999 Jun;6(6):535-9. doi: 10.1038/9304. Nat Struct Biol. 1999. PMID: 10360355

3

X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution.

Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M. Egli M, et al. Biopolymers. 1998;48(4):234-52. doi: 10.1002/(SICI)1097-0282(1998)48:4<234::AID-BIP4>3.0.CO;2-H. Biopolymers. 1998. PMID: 10699842

4

Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.

Tereshko V, Wilds CJ, Minasov G, Prakash TP, Maier MA, Howard A, Wawrzak Z, Manoharan M, Egli M. Tereshko V, et al. Among authors: egli m. Nucleic Acids Res. 2001 Mar 1;29(5):1208-15. doi: 10.1093/nar/29.5.1208. Nucleic Acids Res. 2001. PMID: 11222771 Free PMC article.

5

Direct observation of a cytosine analogue that forms five hydrogen bonds to guanosine: guanidino G-clamp.

Wilds CJ, Maier MA, Tereshko V, Manoharan M, Egli M. Wilds CJ, et al. Among authors: egli m. Angew Chem Int Ed Engl. 2002 Jan 4;41(1):115-7. doi: 10.1002/1521-3773(20020104)41:1<115::aid-anie115>3.0.co;2-r. Angew Chem Int Ed Engl. 2002. PMID: 12491456 No abstract available.

6

Why does TNA cross-pair more strongly with RNA than with DNA? an answer from X-ray analysis.

Pallan PS, Wilds CJ, Wawrzak Z, Krishnamurthy R, Eschenmoser A, Egli M. Pallan PS, et al. Among authors: egli m. Angew Chem Int Ed Engl. 2003;42(47):5893-5. doi: 10.1002/anie.200352553. Angew Chem Int Ed Engl. 2003. PMID: 14673929 No abstract available.

7

Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogues.

Pattanayek R, Sethaphong L, Pan C, Prhavc M, Prakash TP, Manoharan M, Egli M. Pattanayek R, et al. Among authors: egli m. J Am Chem Soc. 2004 Nov 24;126(46):15006-7. doi: 10.1021/ja044637k. J Am Chem Soc. 2004. PMID: 15547979

8

Nucleic acid crystallography: current progress.

Egli M. Egli M. Curr Opin Chem Biol. 2004 Dec;8(6):580-91. doi: 10.1016/j.cbpa.2004.09.004. Curr Opin Chem Biol. 2004. PMID: 15556400 Review.

9

Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2'-O-ribonucleic acid modifications.

Egli M, Minasov G, Tereshko V, Pallan PS, Teplova M, Inamati GB, Lesnik EA, Owens SR, Ross BS, Prakash TP, Manoharan M. Egli M, et al. Biochemistry. 2005 Jun 28;44(25):9045-57. doi: 10.1021/bi050574m. Biochemistry. 2005. PMID: 15966728 Free article.

10

Syntheses of 4'-thioribonucleosides and thermodynamic stability and crystal structure of RNA oligomers with incorporated 4'-thiocytosine.

Haeberli P, Berger I, Pallan PS, Egli M. Haeberli P, et al. Among authors: egli m. Nucleic Acids Res. 2005 Jul 18;33(13):3965-75. doi: 10.1093/nar/gki704. Print 2005. Nucleic Acids Res. 2005. PMID: 16027443 Free PMC article.

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