Maier MA - Search Results

1

Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme.

Li F, Pallan PS, Maier MA, Rajeev KG, Mathieu SL, Kreutz C, Fan Y, Sanghvi J, Micura R, Rozners E, Manoharan M, Egli M. Li F, et al. Among authors: maier ma. Nucleic Acids Res. 2007;35(19):6424-38. doi: 10.1093/nar/gkm664. Epub 2007 Sep 18. Nucleic Acids Res. 2007. PMID: 17881374 Free PMC article.

2

X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution.

Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M. Egli M, et al. Among authors: maier ma. Biopolymers. 1998;48(4):234-52. doi: 10.1002/(SICI)1097-0282(1998)48:4<234::AID-BIP4>3.0.CO;2-H. Biopolymers. 1998. PMID: 10699842

3

Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.

Tereshko V, Wilds CJ, Minasov G, Prakash TP, Maier MA, Howard A, Wawrzak Z, Manoharan M, Egli M. Tereshko V, et al. Among authors: maier ma. Nucleic Acids Res. 2001 Mar 1;29(5):1208-15. doi: 10.1093/nar/29.5.1208. Nucleic Acids Res. 2001. PMID: 11222771 Free PMC article.

4

Inhibition of (cytosine C5)-methyltransferase by oligonucleotides containing flexible (cyclopentane) and conformationally constrained (bicyclo[3.1.0]hexane) abasic sites.

Marquez VE, Wang P, Nicklaus MC, Maier M, Manoharan M, Christman JK, Banavali NK, Mackerell AD Jr. Marquez VE, et al. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):451-9. doi: 10.1081/NCN-100002319. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11563060 Review.

5

Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs.

Sazani P, Kang SH, Maier MA, Wei C, Dillman J, Summerton J, Manoharan M, Kole R. Sazani P, et al. Among authors: maier ma. Nucleic Acids Res. 2001 Oct 1;29(19):3965-74. doi: 10.1093/nar/29.19.3965. Nucleic Acids Res. 2001. PMID: 11574678 Free PMC article.

6

High-affinity peptide nucleic acid oligomers containing tricyclic cytosine analogues.

Rajeev KG, Maier MA, Lesnik EA, Manoharan M. Rajeev KG, et al. Among authors: maier ma. Org Lett. 2002 Dec 12;4(25):4395-8. doi: 10.1021/ol027026a. Org Lett. 2002. PMID: 12465896

7

Direct observation of a cytosine analogue that forms five hydrogen bonds to guanosine: guanidino G-clamp.

Wilds CJ, Maier MA, Tereshko V, Manoharan M, Egli M. Wilds CJ, et al. Among authors: maier ma. Angew Chem Int Ed Engl. 2002 Jan 4;41(1):115-7. doi: 10.1002/1521-3773(20020104)41:1<115::aid-anie115>3.0.co;2-r. Angew Chem Int Ed Engl. 2002. PMID: 12491456 No abstract available.

8

Synthesis and characterization of oligonucleotides containing conformationally constrained bicyclo[3.1.0]hexane pseudosugar analogs.

Maier MA, Choi Y, Gaus H, Barchi JJ Jr, Marquez VE, Manoharan M. Maier MA, et al. Nucleic Acids Res. 2004 Jul 9;32(12):3642-50. doi: 10.1093/nar/gkh667. Print 2004. Nucleic Acids Res. 2004. PMID: 15247346 Free PMC article.

9

Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates.

Frank-Kamenetsky M, Grefhorst A, Anderson NN, Racie TS, Bramlage B, Akinc A, Butler D, Charisse K, Dorkin R, Fan Y, Gamba-Vitalo C, Hadwiger P, Jayaraman M, John M, Jayaprakash KN, Maier M, Nechev L, Rajeev KG, Read T, Röhl I, Soutschek J, Tan P, Wong J, Wang G, Zimmermann T, de Fougerolles A, Vornlocher HP, Langer R, Anderson DG, Manoharan M, Koteliansky V, Horton JD, Fitzgerald K. Frank-Kamenetsky M, et al. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11915-20. doi: 10.1073/pnas.0805434105. Epub 2008 Aug 11. Proc Natl Acad Sci U S A. 2008. PMID: 18695239 Free PMC article.

10

Direct CNS delivery of siRNA mediates robust silencing in oligodendrocytes.

Querbes W, Ge P, Zhang W, Fan Y, Costigan J, Charisse K, Maier M, Nechev L, Manoharan M, Kotelianski V, Sah DW. Querbes W, et al. Oligonucleotides. 2009 Mar;19(1):23-29. doi: 10.1089/oli.2008.0165. Oligonucleotides. 2009. PMID: 19093781

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