Weiss MA - Search Results

1

The A-chain of insulin contacts the insert domain of the insulin receptor. Photo-cross-linking and mutagenesis of a diabetes-related crevice.

Huang K, Chan SJ, Hua QX, Chu YC, Wang RY, Klaproth B, Jia W, Whittaker J, De Meyts P, Nakagawa SH, Steiner DF, Katsoyannis PG, Weiss MA. Huang K, et al. Among authors: weiss ma. J Biol Chem. 2007 Nov 30;282(48):35337-49. doi: 10.1074/jbc.M705996200. Epub 2007 Sep 20. J Biol Chem. 2007. PMID: 17884811 Free article.

2

A cavity-forming mutation in insulin induces segmental unfolding of a surrounding alpha-helix.

Xu B, Hua QX, Nakagawa SH, Jia W, Chu YC, Katsoyannis PG, Weiss MA. Xu B, et al. Among authors: weiss ma. Protein Sci. 2002 Jan;11(1):104-16. doi: 10.1110/ps.32102. Protein Sci. 2002. PMID: 11742127 Free PMC article.

3

Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor.

Weiss MA, Wan Z, Zhao M, Chu YC, Nakagawa SH, Burke GT, Jia W, Hellmich R, Katsoyannis PG. Weiss MA, et al. J Mol Biol. 2002 Jan 11;315(2):103-11. doi: 10.1006/jmbi.2001.5224. J Mol Biol. 2002. PMID: 11779231

4

Protein structure and the spandrels of San Marco: insulin's receptor-binding surface is buttressed by an invariant leucine essential for its stability.

Weiss MA, Nakagawa SH, Jia W, Xu B, Hua QX, Chu YC, Wang RY, Katsoyannis PG. Weiss MA, et al. Biochemistry. 2002 Jan 22;41(3):809-19. doi: 10.1021/bi011839+. Biochemistry. 2002. PMID: 11790102

5

Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue.

Xu B, Hua QX, Nakagawa SH, Jia W, Chu YC, Katsoyannis PG, Weiss MA. Xu B, et al. Among authors: weiss ma. J Mol Biol. 2002 Feb 22;316(3):435-41. doi: 10.1006/jmbi.2001.5377. J Mol Biol. 2002. PMID: 11866509

6

Mechanism of insulin chain combination. Asymmetric roles of A-chain alpha-helices in disulfide pairing.

Hua QX, Chu YC, Jia W, Phillips NF, Wang RY, Katsoyannis PG, Weiss MA. Hua QX, et al. Among authors: weiss ma. J Biol Chem. 2002 Nov 8;277(45):43443-53. doi: 10.1074/jbc.M206107200. Epub 2002 Aug 23. J Biol Chem. 2002. PMID: 12196530 Free article.

7

Mechanism of insulin fibrillation: the structure of insulin under amyloidogenic conditions resembles a protein-folding intermediate.

Hua QX, Weiss MA. Hua QX, et al. Among authors: weiss ma. J Biol Chem. 2004 May 14;279(20):21449-60. doi: 10.1074/jbc.M314141200. Epub 2004 Feb 26. J Biol Chem. 2004. PMID: 14988398 Free article.

8

Diabetes-associated mutations in insulin identify invariant receptor contacts.

Xu B, Hu SQ, Chu YC, Wang S, Wang RY, Nakagawa SH, Katsoyannis PG, Weiss MA. Xu B, et al. Among authors: weiss ma. Diabetes. 2004 Jun;53(6):1599-602. doi: 10.2337/diabetes.53.6.1599. Diabetes. 2004. PMID: 15161767

9

Diabetes-associated mutations in insulin: consecutive residues in the B chain contact distinct domains of the insulin receptor.

Xu B, Hu SQ, Chu YC, Huang K, Nakagawa SH, Whittaker J, Katsoyannis PG, Weiss MA. Xu B, et al. Among authors: weiss ma. Biochemistry. 2004 Jul 6;43(26):8356-72. doi: 10.1021/bi0497796. Biochemistry. 2004. PMID: 15222748

10

How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor.

Huang K, Xu B, Hu SQ, Chu YC, Hua QX, Qu Y, Li B, Wang S, Wang RY, Nakagawa SH, Theede AM, Whittaker J, De Meyts P, Katsoyannis PG, Weiss MA. Huang K, et al. Among authors: weiss ma. J Mol Biol. 2004 Aug 6;341(2):529-50. doi: 10.1016/j.jmb.2004.05.023. J Mol Biol. 2004. PMID: 15276842

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