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Page 1
N-hydroxy-N'-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxy-benzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: synergistic antitumor activity with arabinofuranosylcytosine.
Saiko P, Ozsvar-Kozma M, Bernhaus A, Jaschke M, Graser G, Lackner A, Grusch M, Horvath Z, Madlener S, Krupitza G, Handler N, Erker T, Jaeger W, Fritzer-Szekeres M, Szekeres T. Saiko P, et al. Among authors: graser g. Int J Oncol. 2007 Nov;31(5):1261-6. Int J Oncol. 2007. PMID: 17912455
A novel N-hydroxy-N'-aminoguanidine derivative inhibits ribonucleotide reductase activity: Effects in human HL-60 promyelocytic leukemia cells and synergism with arabinofuranosylcytosine (Ara-C).
Saiko P, Graser G, Giessrigl B, Lackner A, Grusch M, Krupitza G, Basu A, Sinha BN, Jayaprakash V, Jaeger W, Fritzer-Szekeres M, Szekeres T. Saiko P, et al. Among authors: graser g. Biochem Pharmacol. 2011 Jan 1;81(1):50-9. doi: 10.1016/j.bcp.2010.09.006. Epub 2010 Sep 16. Biochem Pharmacol. 2011. PMID: 20849828
Combination effects of digalloylresveratrol with arabinofuranosylcytosine and difluorodeoxycytidine in human leukemia and pancreatic cancer cells.
Saiko P, Graser G, Madlener S, Schwarz S, Krupitza G, Jaeger W, Somepalli V, Golakoti T, Fritzer-Szekeres M, Szekeres T. Saiko P, et al. Among authors: graser g. Nucleosides Nucleotides Nucleic Acids. 2011 Dec;30(12):1190-6. doi: 10.1080/15257770.2011.596497. Nucleosides Nucleotides Nucleic Acids. 2011. PMID: 22132974
Epigallocatechin gallate, ellagic acid, and rosmarinic acid perturb dNTP pools and inhibit de novo DNA synthesis and proliferation of human HL-60 promyelocytic leukemia cells: Synergism with arabinofuranosylcytosine.
Saiko P, Steinmann MT, Schuster H, Graser G, Bressler S, Giessrigl B, Lackner A, Grusch M, Krupitza G, Bago-Horvath Z, Jaeger W, Fritzer-Szekeres M, Szekeres T. Saiko P, et al. Among authors: graser g. Phytomedicine. 2015 Jan 15;22(1):213-22. doi: 10.1016/j.phymed.2014.11.017. Epub 2014 Dec 3. Phytomedicine. 2015. PMID: 25636891
Ribose-modified purine nucleosides as ribonucleotide reductase inhibitors. Synthesis, antitumor activity, and molecular modeling of N6-substituted 3'-C-methyladenosine derivatives.
Cappellacci L, Franchetti P, Vita P, Petrelli R, Lavecchia A, Jayaram HN, Saiko P, Graser G, Szekeres T, Grifantini M. Cappellacci L, et al. Among authors: graser g. J Med Chem. 2008 Jul 24;51(14):4260-9. doi: 10.1021/jm800205c. Epub 2008 Jun 28. J Med Chem. 2008. PMID: 18588281
Methyl-2-arylidene hydrazinecarbodithioates: synthesis and biological activity.
Mahapatra M, Kulandaivelu U, Saiko P, Graser G, Szekeres T, Andrei G, Snoeck R, Balzarini J, Jayaprakash V. Mahapatra M, et al. Among authors: graser g. Chem Zvesti. 2013;67(6):650-656. doi: 10.2478/s11696-013-0346-4. Epub 2013 Feb 19. Chem Zvesti. 2013. PMID: 32214621 Free PMC article.
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