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Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling.
Blaney Davidson EN, Vitters EL, van Lent PL, van de Loo FA, van den Berg WB, van der Kraan PM. Blaney Davidson EN, et al. Among authors: van der kraan pm, van lent pl, van de loo fa, van den berg wb. Arthritis Res Ther. 2007;9(5):R102. doi: 10.1186/ar2305. Arthritis Res Ther. 2007. PMID: 17922907 Free PMC article.
Increased expression of Fcgamma receptors II and III on macrophages of rheumatoid arthritis patients results in higher production of tumor necrosis factor alpha and matrix metalloproteinase.
Blom AB, Radstake TR, Holthuysen AE, Slöetjes AW, Pesman GJ, Sweep FG, van de Loo FA, Joosten LA, Barrera P, van Lent PL, van den Berg WB. Blom AB, et al. Among authors: van lent pl, van de loo fa, van den berg wb. Arthritis Rheum. 2003 Apr;48(4):1002-14. doi: 10.1002/art.10871. Arthritis Rheum. 2003. PMID: 12687542 Free article.
Local IL-13 gene transfer prior to immune-complex arthritis inhibits chondrocyte death and matrix-metalloproteinase-mediated cartilage matrix degradation despite enhanced joint inflammation.
Nabbe KC, van Lent PL, Holthuysen AE, Sloëtjes AW, Koch AE, Radstake TR, van den Berg WB. Nabbe KC, et al. Among authors: van lent pl, van den berg wb. Arthritis Res Ther. 2005;7(2):R392-401. doi: 10.1186/ar1502. Epub 2005 Jan 26. Arthritis Res Ther. 2005. PMID: 15743487 Free PMC article.
NADPH-oxidase-driven oxygen radical production determines chondrocyte death and partly regulates metalloproteinase-mediated cartilage matrix degradation during interferon-gamma-stimulated immune complex arthritis.
van Lent PL, Nabbe KC, Blom AB, Sloetjes A, Holthuysen AE, Kolls J, Van De Loo FA, Holland SM, Van Den Berg WB. van Lent PL, et al. Among authors: van de loo fa, van den berg wb. Arthritis Res Ther. 2005;7(4):R885-95. doi: 10.1186/ar1760. Epub 2005 May 20. Arthritis Res Ther. 2005. PMID: 15987491 Free PMC article.
Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3.
Blom AB, van Lent PL, Libregts S, Holthuysen AE, van der Kraan PM, van Rooijen N, van den Berg WB. Blom AB, et al. Among authors: van der kraan pm, van rooijen n, van lent pl, van den berg wb. Arthritis Rheum. 2007 Jan;56(1):147-57. doi: 10.1002/art.22337. Arthritis Rheum. 2007. PMID: 17195217 Free article.
Osteophytes: relevance and biology.
van der Kraan PM, van den Berg WB. van der Kraan PM, et al. Among authors: van den berg wb. Osteoarthritis Cartilage. 2007 Mar;15(3):237-44. doi: 10.1016/j.joca.2006.11.006. Epub 2007 Jan 3. Osteoarthritis Cartilage. 2007. PMID: 17204437 Free article. Review.
Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: prominent role of Wnt-induced signaling protein 1.
Blom AB, Brockbank SM, van Lent PL, van Beuningen HM, Geurts J, Takahashi N, van der Kraan PM, van de Loo FA, Schreurs BW, Clements K, Newham P, van den Berg WB. Blom AB, et al. Among authors: van der kraan pm, van lent pl, van de loo fa, van beuningen hm, van den berg wb. Arthritis Rheum. 2009 Feb;60(2):501-12. doi: 10.1002/art.24247. Arthritis Rheum. 2009. PMID: 19180479 Free article.
596 results