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Page 1
Antibody-mediated blockade of integrin alpha v beta 6 inhibits tumor progression in vivo by a transforming growth factor-beta-regulated mechanism.
Van Aarsen LA, Leone DR, Ho S, Dolinski BM, McCoon PE, LePage DJ, Kelly R, Heaney G, Rayhorn P, Reid C, Simon KJ, Horan GS, Tao N, Gardner HA, Skelly MM, Gown AM, Thomas GJ, Weinreb PH, Fawell SE, Violette SM. Van Aarsen LA, et al. Among authors: dolinski bm. Cancer Res. 2008 Jan 15;68(2):561-70. doi: 10.1158/0008-5472.CAN-07-2307. Cancer Res. 2008. PMID: 18199553
Overexpression of the alphavbeta6 integrin in endometrial cancer.
Hecht JL, Dolinski BM, Gardner HA, Violette SM, Weinreb PH. Hecht JL, et al. Among authors: dolinski bm. Appl Immunohistochem Mol Morphol. 2008 Dec;16(6):543-7. doi: 10.1097/PAI.0b013e31816bc5ee. Appl Immunohistochem Mol Morphol. 2008. PMID: 18698261
Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse.
Hahm K, Lukashev ME, Luo Y, Yang WJ, Dolinski BM, Weinreb PH, Simon KJ, Chun Wang L, Leone DR, Lobb RR, McCrann DJ, Allaire NE, Horan GS, Fogo A, Kalluri R, Shield CF 3rd, Sheppard D, Gardner HA, Violette SM. Hahm K, et al. Among authors: dolinski bm. Am J Pathol. 2007 Jan;170(1):110-25. doi: 10.2353/ajpath.2007.060158. Am J Pathol. 2007. PMID: 17200187 Free PMC article.
An assessment of the mechanistic differences between two integrin alpha 4 beta 1 inhibitors, the monoclonal antibody TA-2 and the small molecule BIO5192, in rat experimental autoimmune encephalomyelitis.
Leone DR, Giza K, Gill A, Dolinski BM, Yang W, Perper S, Scott DM, Lee WC, Cornebise M, Wortham K, Nickerson-Nutter C, Chen LL, LePage D, Spell JC, Whalley ET, Petter RC, Adams SP, Lobb RR, Pepinsky RB. Leone DR, et al. Among authors: dolinski bm. J Pharmacol Exp Ther. 2003 Jun;305(3):1150-62. doi: 10.1124/jpet.102.047332. Epub 2003 Mar 6. J Pharmacol Exp Ther. 2003. PMID: 12626659
Role of alphavbeta6 integrin in acute biliary fibrosis.
Wang B, Dolinski BM, Kikuchi N, Leone DR, Peters MG, Weinreb PH, Violette SM, Bissell DM. Wang B, et al. Among authors: dolinski bm. Hepatology. 2007 Nov;46(5):1404-12. doi: 10.1002/hep.21849. Hepatology. 2007. PMID: 17924447 Free PMC article.
Inhibition of αvβ5 Integrin Attenuates Vascular Permeability and Protects against Renal Ischemia-Reperfusion Injury.
McCurley A, Alimperti S, Campos-Bilderback SB, Sandoval RM, Calvino JE, Reynolds TL, Quigley C, Mugford JW, Polacheck WJ, Gomez IG, Dovey J, Marsh G, Huang A, Qian F, Weinreb PH, Dolinski BM, Moore S, Duffield JS, Chen CS, Molitoris BA, Violette SM, Crackower MA. McCurley A, et al. Among authors: dolinski bm. J Am Soc Nephrol. 2017 Jun;28(6):1741-1752. doi: 10.1681/ASN.2016020200. Epub 2017 Jan 6. J Am Soc Nephrol. 2017. PMID: 28062569 Free PMC article.
Design, synthesis, and analysis of a polyethelene glycol-modified (PEGylated) small molecule inhibitor of integrin {alpha}4{beta}1 with improved pharmaceutical properties.
Pepinsky RB, Lee WC, Cornebise M, Gill A, Wortham K, Chen LL, Leone DR, Giza K, Dolinski BM, Perper S, Nickerson-Nutter C, Lepage D, Chakraborty A, Whalley ET, Petter RC, Adams SP, Lobb RR, Scott DM. Pepinsky RB, et al. Among authors: dolinski bm. J Pharmacol Exp Ther. 2005 Feb;312(2):742-50. doi: 10.1124/jpet.104.075648. Epub 2004 Oct 14. J Pharmacol Exp Ther. 2005. PMID: 15485895
20 results