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Genome maps across 26 human populations reveal population-specific patterns of structural variation.
Levy-Sakin M, Pastor S, Mostovoy Y, Li L, Leung AKY, McCaffrey J, Young E, Lam ET, Hastie AR, Wong KHY, Chung CYL, Ma W, Sibert J, Rajagopalan R, Jin N, Chow EYC, Chu C, Poon A, Lin C, Naguib A, Wang WP, Cao H, Chan TF, Yip KY, Xiao M, Kwok PY. Levy-Sakin M, et al. Among authors: chan tf. Nat Commun. 2019 Mar 4;10(1):1025. doi: 10.1038/s41467-019-08992-7. Nat Commun. 2019. PMID: 30833565 Free PMC article.
OMMA enables population-scale analysis of complex genomic features and phylogenomic relationships from nanochannel-based optical maps.
Leung AK, Liu MC, Li L, Lai YY, Chu C, Kwok PY, Ho PL, Yip KY, Chan TF. Leung AK, et al. Among authors: chan tf. Gigascience. 2019 Jul 1;8(7):giz079. doi: 10.1093/gigascience/giz079. Gigascience. 2019. PMID: 31289833 Free PMC article.
The OMMA software is available at https://github.com/TF-Chan-Lab/OMTools....
The OMMA software is available at https://github.com/TF-Chan-Lab/OMTools....
Rapid DNA mapping by fluorescent single molecule detection.
Xiao M, Phong A, Ha C, Chan TF, Cai D, Leung L, Wan E, Kistler AL, DeRisi JL, Selvin PR, Kwok PY. Xiao M, et al. Among authors: chan tf. Nucleic Acids Res. 2007;35(3):e16. doi: 10.1093/nar/gkl1044. Epub 2006 Dec 14. Nucleic Acids Res. 2007. PMID: 17175538 Free PMC article.
Genome-Wide Structural Variation Detection by Genome Mapping on Nanochannel Arrays.
Mak AC, Lai YY, Lam ET, Kwok TP, Leung AK, Poon A, Mostovoy Y, Hastie AR, Stedman W, Anantharaman T, Andrews W, Zhou X, Pang AW, Dai H, Chu C, Lin C, Wu JJ, Li CM, Li JW, Yim AK, Chan S, Sibert J, Džakula Ž, Cao H, Yiu SM, Chan TF, Yip KY, Xiao M, Kwok PY. Mak AC, et al. Among authors: chan s, chan tf. Genetics. 2016 Jan;202(1):351-62. doi: 10.1534/genetics.115.183483. Epub 2015 Oct 28. Genetics. 2016. PMID: 26510793 Free PMC article.
OMBlast: alignment tool for optical mapping using a seed-and-extend approach.
Leung AK, Kwok TP, Wan R, Xiao M, Kwok PY, Yip KY, Chan TF. Leung AK, et al. Among authors: chan tf. Bioinformatics. 2017 Feb 1;33(3):311-319. doi: 10.1093/bioinformatics/btw620. Bioinformatics. 2017. PMID: 28172448 Free PMC article.
OMBlast can be downloaded from https://github.com/aldenleung/OMBlast and run directly on machines equipped with a Java virtual machine. CONTACT: [email protected] and tf.chan@cuhk.edu.hk SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinform …
OMBlast can be downloaded from https://github.com/aldenleung/OMBlast and run directly on machines equipped with a Java virtual machine. CONT …
OMSV enables accurate and comprehensive identification of large structural variations from nanochannel-based single-molecule optical maps.
Li L, Leung AK, Kwok TP, Lai YYY, Pang IK, Chung GT, Mak ACY, Poon A, Chu C, Li M, Wu JJK, Lam ET, Cao H, Lin C, Sibert J, Yiu SM, Xiao M, Lo KW, Kwok PY, Chan TF, Yip KY. Li L, et al. Among authors: chan tf. Genome Biol. 2017 Dec 1;18(1):230. doi: 10.1186/s13059-017-1356-2. Genome Biol. 2017. PMID: 29195502 Free PMC article.
352 results