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Postoperative hyperoxia (60%) worsens hepatic injury in mice.
Zangl Q, Martignoni A, Jackson SH, Ohta A, Klaunberg B, Kaufmann I, Lukashev D, Ward JM, Sitkovsky M, Thiel M, Choukèr A. Zangl Q, et al. Among authors: lukashev d. Anesthesiology. 2014 Dec;121(6):1217-25. doi: 10.1097/ALN.0000000000000447. Anesthesiology. 2014. PMID: 25225820 Free article.
An orally available, brain penetrant, small molecule lowers huntingtin levels by enhancing pseudoexon inclusion.
Keller CG, Shin Y, Monteys AM, Renaud N, Beibel M, Teider N, Peters T, Faller T, St-Cyr S, Knehr J, Roma G, Reyes A, Hild M, Lukashev D, Theil D, Dales N, Cha JH, Borowsky B, Dolmetsch R, Davidson BL, Sivasankaran R. Keller CG, et al. Among authors: lukashev d. Nat Commun. 2022 Mar 3;13(1):1150. doi: 10.1038/s41467-022-28653-6. Nat Commun. 2022. PMID: 35241644 Free PMC article.
Regulated control of gene therapies by drug-induced splicing.
Monteys AM, Hundley AA, Ranum PT, Tecedor L, Muehlmatt A, Lim E, Lukashev D, Sivasankaran R, Davidson BL. Monteys AM, et al. Among authors: lukashev d. Nature. 2021 Aug;596(7871):291-295. doi: 10.1038/s41586-021-03770-2. Epub 2021 Jul 28. Nature. 2021. PMID: 34321659 Free PMC article.
Equilibrative nucleoside transporter 1 (ENT1) regulates postischemic blood flow during acute kidney injury in mice.
Grenz A, Bauerle JD, Dalton JH, Ridyard D, Badulak A, Tak E, McNamee EN, Clambey E, Moldovan R, Reyes G, Klawitter J, Ambler K, Magee K, Christians U, Brodsky KS, Ravid K, Choi DS, Wen J, Lukashev D, Blackburn MR, Osswald H, Coe IR, Nürnberg B, Haase VH, Xia Y, Sitkovsky M, Eltzschig HK. Grenz A, et al. Among authors: lukashev d. J Clin Invest. 2017 Jun 1;127(6):2438. doi: 10.1172/JCI94890. Epub 2017 Jun 1. J Clin Invest. 2017. PMID: 28569735 Free PMC article. No abstract available.
Immunological mechanisms of the antitumor effects of supplemental oxygenation.
Hatfield SM, Kjaergaard J, Lukashev D, Schreiber TH, Belikoff B, Abbott R, Sethumadhavan S, Philbrook P, Ko K, Cannici R, Thayer M, Rodig S, Kutok JL, Jackson EK, Karger B, Podack ER, Ohta A, Sitkovsky MV. Hatfield SM, et al. Among authors: lukashev d. Sci Transl Med. 2015 Mar 4;7(277):277ra30. doi: 10.1126/scitranslmed.aaa1260. Sci Transl Med. 2015. PMID: 25739764 Free PMC article.
41 results