Schwans JP - Search Results

1

Structural inference of native and partially folded RNA by high-throughput contact mapping.

Das R, Kudaravalli M, Jonikas M, Laederach A, Fong R, Schwans JP, Baker D, Piccirilli JA, Altman RB, Herschlag D. Das R, et al. Among authors: schwans jp. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4144-9. doi: 10.1073/pnas.0709032105. Epub 2008 Mar 5. Proc Natl Acad Sci U S A. 2008. PMID: 18322008 Free PMC article.

2

2'-Fluoro substituents can mimic native 2'-hydroxyls within structured RNA.

Forconi M, Schwans JP, Porecha RH, Sengupta RN, Piccirilli JA, Herschlag D. Forconi M, et al. Among authors: schwans jp. Chem Biol. 2011 Aug 26;18(8):949-54. doi: 10.1016/j.chembiol.2011.07.014. Chem Biol. 2011. PMID: 21867910 Free PMC article.

3

2'-mercaptonucleotide interference reveals regions of close packing within folded RNA molecules.

Schwans JP, Cortez CN, Olvera JM, Piccirilli JA. Schwans JP, et al. J Am Chem Soc. 2003 Aug 20;125(33):10012-8. doi: 10.1021/ja035175y. J Am Chem Soc. 2003. PMID: 12914464

4

A packing-density metric for exploring the interior of folded RNA molecules.

Schwans JP, Li NS, Piccirilli JA. Schwans JP, et al. Angew Chem Int Ed Engl. 2004 Jun 7;43(23):3033-7. doi: 10.1002/anie.200353575. Angew Chem Int Ed Engl. 2004. PMID: 15188472 No abstract available.

5

Determining the catalytic role of remote substrate binding interactions in ketosteroid isomerase.

Schwans JP, Kraut DA, Herschlag D. Schwans JP, et al. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14271-5. doi: 10.1073/pnas.0901032106. Epub 2009 Aug 12. Proc Natl Acad Sci U S A. 2009. PMID: 19706511 Free PMC article.

6

Quantitative, directional measurement of electric field heterogeneity in the active site of ketosteroid isomerase.

Fafarman AT, Sigala PA, Schwans JP, Fenn TD, Herschlag D, Boxer SG. Fafarman AT, et al. Among authors: schwans jp. Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):E299-308. doi: 10.1073/pnas.1111566109. Epub 2012 Jan 17. Proc Natl Acad Sci U S A. 2012. PMID: 22308339 Free PMC article.

7

Use of anion-aromatic interactions to position the general base in the ketosteroid isomerase active site.

Schwans JP, Sunden F, Lassila JK, Gonzalez A, Tsai Y, Herschlag D. Schwans JP, et al. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11308-13. doi: 10.1073/pnas.1206710110. Epub 2013 Jun 24. Proc Natl Acad Sci U S A. 2013. PMID: 23798413 Free PMC article.

8

New strategies for exploring RNA's 2'-OH expose the importance of solvent during group II intron catalysis.

Gordon PM, Fong R, Deb SK, Li NS, Schwans JP, Ye JD, Piccirilli JA. Gordon PM, et al. Among authors: schwans jp. Chem Biol. 2004 Feb;11(2):237-46. doi: 10.1016/j.chembiol.2004.02.011. Chem Biol. 2004. PMID: 15123285

9

Quantitative dissection of hydrogen bond-mediated proton transfer in the ketosteroid isomerase active site.

Sigala PA, Fafarman AT, Schwans JP, Fried SD, Fenn TD, Caaveiro JM, Pybus B, Ringe D, Petsko GA, Boxer SG, Herschlag D. Sigala PA, et al. Among authors: schwans jp. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):E2552-61. doi: 10.1073/pnas.1302191110. Epub 2013 Jun 24. Proc Natl Acad Sci U S A. 2013. PMID: 23798390 Free PMC article.

10

Using unnatural amino acids to probe the energetics of oxyanion hole hydrogen bonds in the ketosteroid isomerase active site.

Natarajan A, Schwans JP, Herschlag D. Natarajan A, et al. Among authors: schwans jp. J Am Chem Soc. 2014 May 28;136(21):7643-54. doi: 10.1021/ja413174b. Epub 2014 May 14. J Am Chem Soc. 2014. PMID: 24787954 Free PMC article.

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