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Page 1
Clinical implications of BRAF mutation in thyroid carcinoma.
Puxeddu E, Durante C, Avenia N, Filetti S, Russo D. Puxeddu E, et al. Among authors: avenia n. Trends Endocrinol Metab. 2008 May-Jun;19(4):138-45. doi: 10.1016/j.tem.2007.12.003. Epub 2008 Mar 11. Trends Endocrinol Metab. 2008. PMID: 18337114 Review.
BRAF(V599E) mutation is the leading genetic event in adult sporadic papillary thyroid carcinomas.
Puxeddu E, Moretti S, Elisei R, Romei C, Pascucci R, Martinelli M, Marino C, Avenia N, Rossi ED, Fadda G, Cavaliere A, Ribacchi R, Falorni A, Pontecorvi A, Pacini F, Pinchera A, Santeusanio F. Puxeddu E, et al. Among authors: avenia n. J Clin Endocrinol Metab. 2004 May;89(5):2414-20. doi: 10.1210/jc.2003-031425. J Clin Endocrinol Metab. 2004. PMID: 15126572
BRAF mutations in papillary thyroid carcinomas inhibit genes involved in iodine metabolism.
Durante C, Puxeddu E, Ferretti E, Morisi R, Moretti S, Bruno R, Barbi F, Avenia N, Scipioni A, Verrienti A, Tosi E, Cavaliere A, Gulino A, Filetti S, Russo D. Durante C, et al. Among authors: avenia n. J Clin Endocrinol Metab. 2007 Jul;92(7):2840-3. doi: 10.1210/jc.2006-2707. Epub 2007 May 8. J Clin Endocrinol Metab. 2007. PMID: 17488796
Genotyping of an Italian papillary thyroid carcinoma cohort revealed high prevalence of BRAF mutations, absence of RAS mutations and allowed the detection of a new mutation of BRAF oncoprotein (BRAF(V599lns)).
Carta C, Moretti S, Passeri L, Barbi F, Avenia N, Cavaliere A, Monacelli M, Macchiarulo A, Santeusanio F, Tartaglia M, Puxeddu E. Carta C, et al. Among authors: avenia n. Clin Endocrinol (Oxf). 2006 Jan;64(1):105-9. doi: 10.1111/j.1365-2265.2005.02401.x. Clin Endocrinol (Oxf). 2006. PMID: 16402937
Modifications in the papillary thyroid cancer gene profile over the last 15 years.
Romei C, Fugazzola L, Puxeddu E, Frasca F, Viola D, Muzza M, Moretti S, Nicolosi ML, Giani C, Cirello V, Avenia N, Rossi S, Vitti P, Pinchera A, Elisei R. Romei C, et al. Among authors: avenia n. J Clin Endocrinol Metab. 2012 Sep;97(9):E1758-65. doi: 10.1210/jc.2012-1269. Epub 2012 Jun 28. J Clin Endocrinol Metab. 2012. PMID: 22745248
Indoleamine 2,3-dioxygenase 1 (IDO1) is up-regulated in thyroid carcinoma and drives the development of an immunosuppressant tumor microenvironment.
Moretti S, Menicali E, Voce P, Morelli S, Cantarelli S, Sponziello M, Colella R, Fallarino F, Orabona C, Alunno A, de Biase D, Bini V, Mameli MG, Filetti S, Gerli R, Macchiarulo A, Melillo RM, Tallini G, Santoro M, Puccetti P, Avenia N, Puxeddu E. Moretti S, et al. Among authors: avenia n. J Clin Endocrinol Metab. 2014 May;99(5):E832-40. doi: 10.1210/jc.2013-3351. Epub 2014 Feb 11. J Clin Endocrinol Metab. 2014. PMID: 24517146
264 results