Jadhav A - Search Results

1

Fluorescence spectroscopic profiling of compound libraries.

Simeonov A, Jadhav A, Thomas CJ, Wang Y, Huang R, Southall NT, Shinn P, Smith J, Austin CP, Auld DS, Inglese J. Simeonov A, et al. Among authors: jadhav a. J Med Chem. 2008 Apr 24;51(8):2363-71. doi: 10.1021/jm701301m. Epub 2008 Mar 26. J Med Chem. 2008. PMID: 18363325

2

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries.

Inglese J, Auld DS, Jadhav A, Johnson RL, Simeonov A, Yasgar A, Zheng W, Austin CP. Inglese J, et al. Among authors: jadhav a. Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11473-8. doi: 10.1073/pnas.0604348103. Epub 2006 Jul 24. Proc Natl Acad Sci U S A. 2006. PMID: 16864780 Free PMC article.

3

Fluorescent protein-based cellular assays analyzed by laser-scanning microplate cytometry in 1536-well plate format.

Auld DS, Johnson RL, Zhang YQ, Veith H, Jadhav A, Yasgar A, Simeonov A, Zheng W, Martinez ED, Westwick JK, Austin CP, Inglese J. Auld DS, et al. Among authors: jadhav a. Methods Enzymol. 2006;414:566-89. doi: 10.1016/S0076-6879(06)14029-X. Methods Enzymol. 2006. PMID: 17110211

4

A high-throughput screen for aggregation-based inhibition in a large compound library.

Feng BY, Simeonov A, Jadhav A, Babaoglu K, Inglese J, Shoichet BK, Austin CP. Feng BY, et al. Among authors: jadhav a. J Med Chem. 2007 May 17;50(10):2385-90. doi: 10.1021/jm061317y. Epub 2007 Apr 21. J Med Chem. 2007. PMID: 17447748

5

Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease.

Zheng W, Padia J, Urban DJ, Jadhav A, Goker-Alpan O, Simeonov A, Goldin E, Auld D, LaMarca ME, Inglese J, Austin CP, Sidransky E. Zheng W, et al. Among authors: jadhav a. Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13192-7. doi: 10.1073/pnas.0705637104. Epub 2007 Aug 1. Proc Natl Acad Sci U S A. 2007. PMID: 17670938 Free PMC article.

6

Dual-fluorophore quantitative high-throughput screen for inhibitors of BRCT-phosphoprotein interaction.

Simeonov A, Yasgar A, Jadhav A, Lokesh GL, Klumpp C, Michael S, Austin CP, Natarajan A, Inglese J. Simeonov A, et al. Among authors: jadhav a. Anal Biochem. 2008 Apr 1;375(1):60-70. doi: 10.1016/j.ab.2007.11.039. Epub 2007 Dec 5. Anal Biochem. 2008. PMID: 18158907 Free PMC article.

7

A quantitative high-throughput screen identifies potential epigenetic modulators of gene expression.

Johnson RL, Huang W, Jadhav A, Austin CP, Inglese J, Martinez ED. Johnson RL, et al. Among authors: jadhav a. Anal Biochem. 2008 Apr 15;375(2):237-48. doi: 10.1016/j.ab.2007.12.028. Epub 2007 Dec 25. Anal Biochem. 2008. PMID: 18211814 Free PMC article.

8

Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade.

Simeonov A, Jadhav A, Sayed AA, Wang Y, Nelson ME, Thomas CJ, Inglese J, Williams DL, Austin CP. Simeonov A, et al. Among authors: jadhav a. PLoS Negl Trop Dis. 2008 Jan 2;2(1):e127. doi: 10.1371/journal.pntd.0000127. PLoS Negl Trop Dis. 2008. PMID: 18235848 Free PMC article.

9

Comprehensive mechanistic analysis of hits from high-throughput and docking screens against beta-lactamase.

Babaoglu K, Simeonov A, Irwin JJ, Nelson ME, Feng B, Thomas CJ, Cancian L, Costi MP, Maltby DA, Jadhav A, Inglese J, Austin CP, Shoichet BK. Babaoglu K, et al. Among authors: jadhav a. J Med Chem. 2008 Apr 24;51(8):2502-11. doi: 10.1021/jm701500e. Epub 2008 Mar 12. J Med Chem. 2008. PMID: 18333608 Free PMC article.

10

Compound cytotoxicity profiling using quantitative high-throughput screening.

Xia M, Huang R, Witt KL, Southall N, Fostel J, Cho MH, Jadhav A, Smith CS, Inglese J, Portier CJ, Tice RR, Austin CP. Xia M, et al. Among authors: jadhav a. Environ Health Perspect. 2008 Mar;116(3):284-91. doi: 10.1289/ehp.10727. Environ Health Perspect. 2008. PMID: 18335092 Free PMC article.

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