Wang Y - Search Results

1

Fluorescence spectroscopic profiling of compound libraries.

Simeonov A, Jadhav A, Thomas CJ, Wang Y, Huang R, Southall NT, Shinn P, Smith J, Austin CP, Auld DS, Inglese J. Simeonov A, et al. Among authors: wang y. J Med Chem. 2008 Apr 24;51(8):2363-71. doi: 10.1021/jm701301m. Epub 2008 Mar 26. J Med Chem. 2008. PMID: 18363325

2

Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade.

Simeonov A, Jadhav A, Sayed AA, Wang Y, Nelson ME, Thomas CJ, Inglese J, Williams DL, Austin CP. Simeonov A, et al. Among authors: wang y. PLoS Negl Trop Dis. 2008 Jan 2;2(1):e127. doi: 10.1371/journal.pntd.0000127. PLoS Negl Trop Dis. 2008. PMID: 18235848 Free PMC article.

3

A grid algorithm for high throughput fitting of dose-response curve data.

Wang Y, Jadhav A, Southal N, Huang R, Nguyen DT. Wang Y, et al. Curr Chem Genomics. 2010 Oct 21;4:57-66. doi: 10.2174/1875397301004010057. Curr Chem Genomics. 2010. PMID: 21331310 Free PMC article.

4

The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics.

Huang R, Southall N, Wang Y, Yasgar A, Shinn P, Jadhav A, Nguyen DT, Austin CP. Huang R, et al. Among authors: wang y. Sci Transl Med. 2011 Apr 27;3(80):80ps16. doi: 10.1126/scitranslmed.3001862. Sci Transl Med. 2011. PMID: 21525397 Free PMC article.

5

Structure-activity relationship studies and biological characterization of human NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.

Duveau DY, Yasgar A, Wang Y, Hu X, Kouznetsova J, Brimacombe KR, Jadhav A, Simeonov A, Thomas CJ, Maloney DJ. Duveau DY, et al. Among authors: wang y. Bioorg Med Chem Lett. 2014 Jan 15;24(2):630-5. doi: 10.1016/j.bmcl.2013.11.081. Epub 2013 Dec 4. Bioorg Med Chem Lett. 2014. PMID: 24360556 Free PMC article.

6

Correction of Microplate Data from High-Throughput Screening.

Wang Y, Huang R. Wang Y, et al. Methods Mol Biol. 2016;1473:123-34. doi: 10.1007/978-1-4939-6346-1_13. Methods Mol Biol. 2016. PMID: 27518630

7

A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models.

Martinez NJ, Rai G, Yasgar A, Lea WA, Sun H, Wang Y, Luci DK, Yang SM, Nishihara K, Takeda S, Sagor M, Earnshaw I, Okada T, Mori K, Wilson K, Riggins GJ, Xia M, Grimaldi M, Jadhav A, Maloney DJ, Simeonov A. Martinez NJ, et al. Among authors: wang y. PLoS One. 2016 Aug 29;11(8):e0161486. doi: 10.1371/journal.pone.0161486. eCollection 2016. PLoS One. 2016. PMID: 27570969 Free PMC article.

8

Prediction of hERG Liability - Using SVM Classification, Bootstrapping and Jackknifing.

Sun H, Huang R, Xia M, Shahane S, Southall N, Wang Y. Sun H, et al. Among authors: wang y. Mol Inform. 2017 Apr;36(4):10.1002/minf.201600126. doi: 10.1002/minf.201600126. Epub 2016 Dec 21. Mol Inform. 2017. PMID: 28000393 Free PMC article.

9

A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity.

Yasgar A, Titus SA, Wang Y, Danchik C, Yang SM, Vasiliou V, Jadhav A, Maloney DJ, Simeonov A, Martinez NJ. Yasgar A, et al. Among authors: wang y. PLoS One. 2017 Jan 27;12(1):e0170937. doi: 10.1371/journal.pone.0170937. eCollection 2017. PLoS One. 2017. PMID: 28129349 Free PMC article.

10

The Toxmatrix: Chemo-Genomic Profiling Identifies Interactions That Reveal Mechanisms of Toxicity.

Tong ZB, Huang R, Wang Y, Klumpp-Thomas CA, Braisted JC, Itkin Z, Shinn P, Xia M, Simeonov A, Gerhold DL. Tong ZB, et al. Among authors: wang y. Chem Res Toxicol. 2018 Feb 19;31(2):127-136. doi: 10.1021/acs.chemrestox.7b00290. Epub 2017 Dec 4. Chem Res Toxicol. 2018. PMID: 29156121 Free PMC article.

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