Tirona RG - Search Results

1

Breast cancer resistance protein (ABCG2) and drug disposition: intestinal expression, polymorphisms and sulfasalazine as an in vivo probe.

Urquhart BL, Ware JA, Tirona RG, Ho RH, Leake BF, Schwarz UI, Zaher H, Palandra J, Gregor JC, Dresser GK, Kim RB. Urquhart BL, et al. Among authors: tirona rg. Pharmacogenet Genomics. 2008 May;18(5):439-48. doi: 10.1097/FPC.0b013e3282f974dc. Pharmacogenet Genomics. 2008. PMID: 18408567 Free PMC article.

2

Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans.

Tirona RG, Leake BF, Merino G, Kim RB. Tirona RG, et al. J Biol Chem. 2001 Sep 21;276(38):35669-75. doi: 10.1074/jbc.M103792200. Epub 2001 Jul 26. J Biol Chem. 2001. PMID: 11477075 Free article.

3

Transport of the sulfated, amidated bile acid, sulfolithocholyltaurine, into rat hepatocytes is mediated by Oatp1 and Oatp2.

Meng LJ, Wang P, Wolkoff AW, Kim RB, Tirona RG, Hofmann AF, Pang KS. Meng LJ, et al. Among authors: tirona rg. Hepatology. 2002 May;35(5):1031-40. doi: 10.1053/jhep.2002.32667. Hepatology. 2002. PMID: 11981753

4

Pharmacogenomics of organic anion-transporting polypeptides (OATP).

Tirona RG, Kim RB. Tirona RG, et al. Adv Drug Deliv Rev. 2002 Nov 18;54(10):1343-52. doi: 10.1016/s0169-409x(02)00077-7. Adv Drug Deliv Rev. 2002. PMID: 12406649 Review.

5

Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation.

Tirona RG, Leake BF, Wolkoff AW, Kim RB. Tirona RG, et al. J Pharmacol Exp Ther. 2003 Jan;304(1):223-8. doi: 10.1124/jpet.102.043026. J Pharmacol Exp Ther. 2003. PMID: 12490595

6

The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.

Tirona RG, Lee W, Leake BF, Lan LB, Cline CB, Lamba V, Parviz F, Duncan SA, Inoue Y, Gonzalez FJ, Schuetz EG, Kim RB. Tirona RG, et al. Nat Med. 2003 Feb;9(2):220-4. doi: 10.1038/nm815. Epub 2003 Jan 6. Nat Med. 2003. PMID: 12514743

7

Pharmacogenetics of ATP-binding cassette transporters in cancer and chemotherapy.

Lockhart AC, Tirona RG, Kim RB. Lockhart AC, et al. Among authors: tirona rg. Mol Cancer Ther. 2003 Jul;2(7):685-98. Mol Cancer Ther. 2003. PMID: 12883042 Review.

8

Identification of amino acids in rat pregnane X receptor that determine species-specific activation.

Tirona RG, Leake BF, Podust LM, Kim RB. Tirona RG, et al. Mol Pharmacol. 2004 Jan;65(1):36-44. doi: 10.1124/mol.65.1.36. Mol Pharmacol. 2004. PMID: 14722235

9

Pharmacogenomics of the OATP and OAT families.

Marzolini C, Tirona RG, Kim RB. Marzolini C, et al. Among authors: tirona rg. Pharmacogenomics. 2004 Apr;5(3):273-82. doi: 10.1517/phgs.5.3.273.29831. Pharmacogenomics. 2004. PMID: 15102542 Review.

10

Nuclear receptors and drug disposition gene regulation.

Tirona RG, Kim RB. Tirona RG, et al. J Pharm Sci. 2005 Jun;94(6):1169-86. doi: 10.1002/jps.20324. J Pharm Sci. 2005. PMID: 15858847 Review.

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