Hughes A - Search Results

1

High sensitivity of human leukocyte antigen-b*5701 as a marker for immunologically confirmed abacavir hypersensitivity in white and black patients.

Saag M, Balu R, Phillips E, Brachman P, Martorell C, Burman W, Stancil B, Mosteller M, Brothers C, Wannamaker P, Hughes A, Sutherland-Phillips D, Mallal S, Shaefer M; Study of Hypersensitivity to Abacavir and Pharmacogenetic Evaluation Study Team. Saag M, et al. Among authors: hughes a. Clin Infect Dis. 2008 Apr 1;46(7):1111-8. doi: 10.1086/529382. Clin Infect Dis. 2008. PMID: 18444831 Free article.

2

HLA-B*5701 screening for hypersensitivity to abacavir.

Mallal S, Phillips E, Carosi G, Molina JM, Workman C, Tomazic J, Jägel-Guedes E, Rugina S, Kozyrev O, Cid JF, Hay P, Nolan D, Hughes S, Hughes A, Ryan S, Fitch N, Thorborn D, Benbow A; PREDICT-1 Study Team. Mallal S, et al. Among authors: hughes s, hughes a. N Engl J Med. 2008 Feb 7;358(6):568-79. doi: 10.1056/NEJMoa0706135. N Engl J Med. 2008. PMID: 18256392 Free article. Clinical Trial.

3

Pharmacogenetics of hypersensitivity to abacavir: from PGx hypothesis to confirmation to clinical utility.

Hughes AR, Spreen WR, Mosteller M, Warren LL, Lai EH, Brothers CH, Cox C, Nelsen AJ, Hughes S, Thorborn DE, Stancil B, Hetherington SV, Burns DK, Roses AD. Hughes AR, et al. Among authors: hughes s. Pharmacogenomics J. 2008 Dec;8(6):365-74. doi: 10.1038/tpj.2008.3. Epub 2008 Mar 11. Pharmacogenomics J. 2008. PMID: 18332899 Review.

4

Genetic association studies to detect adverse drug reactions: abacavir hypersensitivity as an example.

Hughes AR, Brothers CH, Mosteller M, Spreen WR, Burns DK. Hughes AR, et al. Pharmacogenomics. 2009 Feb;10(2):225-33. doi: 10.2217/14622416.10.2.225. Pharmacogenomics. 2009. PMID: 19207023 Review.

5

Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some, but not all, populations.

Hughes AR, Mosteller M, Bansal AT, Davies K, Haneline SA, Lai EH, Nangle K, Scott T, Spreen WR, Warren LL, Roses AD; CNA30027 Study Team; CNA30032 Study Team. Hughes AR, et al. Pharmacogenomics. 2004 Mar;5(2):203-11. doi: 10.1517/phgs.5.2.203.27481. Pharmacogenomics. 2004. PMID: 15016610

6

PREDICT-1 (CNA106030): the first powered, prospective trial of pharmacogenetic screening to reduce drug adverse events.

Hughes S, Hughes A, Brothers C, Spreen W, Thorborn D; CNA106030 Study Team. Hughes S, et al. Among authors: hughes a. Pharm Stat. 2008 Apr-Jun;7(2):121-9. doi: 10.1002/pst.286. Pharm Stat. 2008. PMID: 17534855

7

Genetic variations in HLA-B region and hypersensitivity reactions to abacavir.

Hetherington S, Hughes AR, Mosteller M, Shortino D, Baker KL, Spreen W, Lai E, Davies K, Handley A, Dow DJ, Fling ME, Stocum M, Bowman C, Thurmond LM, Roses AD. Hetherington S, et al. Among authors: hughes ar. Lancet. 2002 Mar 30;359(9312):1121-2. doi: 10.1016/S0140-6736(02)08158-8. Lancet. 2002. PMID: 11943262

8

Distribution of HLA-B alleles in a Ugandan HIV-infected adult population: NORA pharmacogenetic substudy of DART.

Munderi P, Snowden WB, Walker AS, Kityo C, Mosteller M, Kabuye G, Thoofer NK, Ssali F, Gilks CF, Hughes AR; DART Trial Team. Munderi P, et al. Trop Med Int Health. 2011 Feb;16(2):200-4. doi: 10.1111/j.1365-3156.2010.02688.x. Epub 2010 Nov 23. Trop Med Int Health. 2011. PMID: 21091860 Free article. Clinical Trial.

9

Use of pairwise marker combination and recursive partitioning in a pharmacogenetic genome-wide scan.

Warren LL, Hughes AR, Lai EH, Zaykin DV, Haneline SA, Bansal AT, Wooster AW, Spreen WR, Hernandez JE, Scott TR, Roses AD, Mosteller M; CNA30027 and CNA30032 study teams. Warren LL, et al. Among authors: hughes ar. Pharmacogenomics J. 2007 Jun;7(3):180-9. doi: 10.1038/sj.tpj.6500414. Epub 2006 Sep 12. Pharmacogenomics J. 2007. PMID: 16969363

10

Medical applications of haplotype-based SNP maps: learning to walk before we run.

Lai E, Bowman C, Bansal A, Hughes A, Mosteller M, Roses AD. Lai E, et al. Among authors: hughes a. Nat Genet. 2002 Nov;32(3):353. doi: 10.1038/ng1102-353. Nat Genet. 2002. PMID: 12410232 No abstract available.

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