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T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.
Sauer S, Bruno L, Hertweck A, Finlay D, Leleu M, Spivakov M, Knight ZA, Cobb BS, Cantrell D, O'Connor E, Shokat KM, Fisher AG, Merkenschlager M. Sauer S, et al. Among authors: shokat km. Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7797-802. doi: 10.1073/pnas.0800928105. Epub 2008 May 28. Proc Natl Acad Sci U S A. 2008. PMID: 18509048 Free PMC article.
Chemically targeting the PI3K family.
Knight ZA, Shokat KM. Knight ZA, et al. Among authors: shokat km. Biochem Soc Trans. 2007 Apr;35(Pt 2):245-9. doi: 10.1042/BST0350245. Biochem Soc Trans. 2007. PMID: 17371250
EGFR signals to mTOR through PKC and independently of Akt in glioma.
Fan QW, Cheng C, Knight ZA, Haas-Kogan D, Stokoe D, James CD, McCormick F, Shokat KM, Weiss WA. Fan QW, et al. Among authors: shokat km. Sci Signal. 2009 Jan 27;2(55):ra4. doi: 10.1126/scisignal.2000014. Sci Signal. 2009. PMID: 19176518 Free PMC article.
394 results