Kaufman RJ - Search Results

1

Novel function of PERK as a mediator of force-induced apoptosis.

Mak BC, Wang Q, Laschinger C, Lee W, Ron D, Harding HP, Kaufman RJ, Scheuner D, Austin RC, McCulloch CA. Mak BC, et al. Among authors: kaufman rj. J Biol Chem. 2008 Aug 22;283(34):23462-72. doi: 10.1074/jbc.M803194200. Epub 2008 Jun 11. J Biol Chem. 2008. PMID: 18550523 Free PMC article.

2

Double-stranded RNA-dependent protein kinase phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 mediates apoptosis.

Scheuner D, Patel R, Wang F, Lee K, Kumar K, Wu J, Nilsson A, Karin M, Kaufman RJ. Scheuner D, et al. Among authors: kaufman rj. J Biol Chem. 2006 Jul 28;281(30):21458-21468. doi: 10.1074/jbc.M603784200. Epub 2006 May 22. J Biol Chem. 2006. PMID: 16717090 Free article.

3

Integrated stress response modulates cellular redox state via induction of cystathionine γ-lyase: cross-talk between integrated stress response and thiol metabolism.

Dickhout JG, Carlisle RE, Jerome DE, Mohammed-Ali Z, Jiang H, Yang G, Mani S, Garg SK, Banerjee R, Kaufman RJ, Maclean KN, Wang R, Austin RC. Dickhout JG, et al. Among authors: kaufman rj. J Biol Chem. 2012 Mar 2;287(10):7603-14. doi: 10.1074/jbc.M111.304576. Epub 2012 Jan 3. J Biol Chem. 2012. PMID: 22215680 Free PMC article.

4

Ultraviolet light activates NFkappaB through translational inhibition of IkappaBalpha synthesis.

Wu S, Tan M, Hu Y, Wang JL, Scheuner D, Kaufman RJ. Wu S, et al. Among authors: kaufman rj. J Biol Chem. 2004 Aug 13;279(33):34898-902. doi: 10.1074/jbc.M405616200. Epub 2004 Jun 7. J Biol Chem. 2004. PMID: 15184376 Free article.

5

Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation.

Reddy RK, Mao C, Baumeister P, Austin RC, Kaufman RJ, Lee AS. Reddy RK, et al. Among authors: kaufman rj. J Biol Chem. 2003 Jun 6;278(23):20915-24. doi: 10.1074/jbc.M212328200. Epub 2003 Mar 28. J Biol Chem. 2003. PMID: 12665508 Free article.

6

Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes.

Song B, Scheuner D, Ron D, Pennathur S, Kaufman RJ. Song B, et al. Among authors: kaufman rj. J Clin Invest. 2008 Oct;118(10):3378-89. doi: 10.1172/JCI34587. J Clin Invest. 2008. PMID: 18776938 Free PMC article.

7

Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2.

Deng J, Lu PD, Zhang Y, Scheuner D, Kaufman RJ, Sonenberg N, Harding HP, Ron D. Deng J, et al. Among authors: kaufman rj. Mol Cell Biol. 2004 Dec;24(23):10161-8. doi: 10.1128/MCB.24.23.10161-10168.2004. Mol Cell Biol. 2004. PMID: 15542827 Free PMC article.

8

ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth.

Bi M, Naczki C, Koritzinsky M, Fels D, Blais J, Hu N, Harding H, Novoa I, Varia M, Raleigh J, Scheuner D, Kaufman RJ, Bell J, Ron D, Wouters BG, Koumenis C. Bi M, et al. Among authors: kaufman rj. EMBO J. 2005 Oct 5;24(19):3470-81. doi: 10.1038/sj.emboj.7600777. Epub 2005 Sep 8. EMBO J. 2005. PMID: 16148948 Free PMC article.

9

TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the cevelopment of atherosclerosis in hyperhomocysteinemia.

Hossain GS, van Thienen JV, Werstuck GH, Zhou J, Sood SK, Dickhout JG, de Koning AB, Tang D, Wu D, Falk E, Poddar R, Jacobsen DW, Zhang K, Kaufman RJ, Austin RC. Hossain GS, et al. Among authors: kaufman rj. J Biol Chem. 2003 Aug 8;278(32):30317-27. doi: 10.1074/jbc.M212897200. Epub 2003 May 8. J Biol Chem. 2003. PMID: 12738777 Free article.

10

Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2.

Lu PD, Jousse C, Marciniak SJ, Zhang Y, Novoa I, Scheuner D, Kaufman RJ, Ron D, Harding HP. Lu PD, et al. Among authors: kaufman rj. EMBO J. 2004 Jan 14;23(1):169-79. doi: 10.1038/sj.emboj.7600030. Epub 2004 Jan 8. EMBO J. 2004. PMID: 14713949 Free PMC article.

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