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729 results

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Page 1
Discovery of novel, potent benzamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) exhibiting oral activity in an enzyme inhibition ex vivo model.
Julian LD, Wang Z, Bostick T, Caille S, Choi R, DeGraffenreid M, Di Y, He X, Hungate RW, Jaen JC, Liu J, Monshouwer M, McMinn D, Rew Y, Sudom A, Sun D, Tu H, Ursu S, Walker N, Yan X, Ye Q, Powers JP. Julian LD, et al. Among authors: choi r. J Med Chem. 2008 Jul 10;51(13):3953-60. doi: 10.1021/jm800310g. Epub 2008 Jun 14. J Med Chem. 2008. PMID: 18553955
Synthesis and optimization of arylsulfonylpiperazines as a novel class of inhibitors of 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1).
Sun D, Wang Z, Cardozo M, Choi R, Degraffenreid M, Di Y, He X, Jaen JC, Labelle M, Liu J, Ma J, Miao S, Sudom A, Tang L, Tu H, Ursu S, Walker N, Yan X, Ye Q, Powers JP. Sun D, et al. Among authors: choi r. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1522-7. doi: 10.1016/j.bmcl.2008.12.114. Epub 2009 Jan 9. Bioorg Med Chem Lett. 2009. PMID: 19181519
Discovery of 6-phenylpyrimido[4,5-b][1,4]oxazines as potent and selective acyl CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitors with in vivo efficacy in rodents.
Fox BM, Sugimoto K, Iio K, Yoshida A, Zhang JK, Li K, Hao X, Labelle M, Smith ML, Rubenstein SM, Ye G, McMinn D, Jackson S, Choi R, Shan B, Ma J, Miao S, Matsui T, Ogawa N, Suzuki M, Kobayashi A, Ozeki H, Okuma C, Ishii Y, Tomimoto D, Furakawa N, Tanaka M, Matsushita M, Takahashi M, Inaba T, Sagawa S, Kayser F. Fox BM, et al. Among authors: choi r. J Med Chem. 2014 Apr 24;57(8):3464-83. doi: 10.1021/jm500135c. Epub 2014 Apr 8. J Med Chem. 2014. PMID: 24670009
Development, construct validity and utility of a cross-culturally adapted Otitis Media-6 (OM-6) questionnaire for urban Aboriginal and/or Torres Strait Islander children: A community consulted project.
Veselinović T, Kickett JC, Kickett HL, Yarran GK, Yarran CT, Swift VM, Morrison NR, Gidgup KJ, Choi RSM, Mulders WHAM, Goulios H, Mancini VO, Brennan-Jones CG. Veselinović T, et al. Among authors: choi rsm. Int J Pediatr Otorhinolaryngol. 2024 Oct 16;186:112140. doi: 10.1016/j.ijporl.2024.112140. Online ahead of print. Int J Pediatr Otorhinolaryngol. 2024. PMID: 39427405 No abstract available.
Cardiolipin deficiency disrupts CoQ redox state and induces steatohepatitis.
Brothwell MJ, Cao 曹国燊 G, Maschek JA, Poss AM, Peterlin AD, Wang 汪立平 L, Baker TB, Shahtout JL, Siripoksup P, Pearce QJ, Johnson JM, Finger FM, Prola A, Pellizzari SA, Hale GL, Manuel AM, Watanabe 渡邉真也 S, Miranda ER, Affolter KE, Tippetts TS, Nikolova LS, Choi 崔蘭煕 RH, Decker ST, Patil M, Catrow JL, Holland WL, Nowinski SM, Lark DS, Fisher-Wellman KH, Mimche PN, Evason KJ, Cox JE, Summers SA, Gerhart-Hines Z, Funai 船井勝彦 K. Brothwell MJ, et al. Among authors: choi rh. bioRxiv [Preprint]. 2024 Oct 10:2024.10.10.617517. doi: 10.1101/2024.10.10.617517. bioRxiv. 2024. PMID: 39416056 Free PMC article. Preprint.
729 results