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Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling.
Liotta F, Angeli R, Cosmi L, Filì L, Manuelli C, Frosali F, Mazzinghi B, Maggi L, Pasini A, Lisi V, Santarlasci V, Consoloni L, Angelotti ML, Romagnani P, Parronchi P, Krampera M, Maggi E, Romagnani S, Annunziato F. Liotta F, et al. Among authors: krampera m. Stem Cells. 2008 Jan;26(1):279-89. doi: 10.1634/stemcells.2007-0454. Epub 2007 Oct 25. Stem Cells. 2008. PMID: 17962701
Mesenchymal stem cells share molecular signature with mesenchymal tumor cells and favor early tumor growth in syngeneic mice.
Galiè M, Konstantinidou G, Peroni D, Scambi I, Marchini C, Lisi V, Krampera M, Magnani P, Merigo F, Montani M, Boschi F, Marzola P, Orrù R, Farace P, Sbarbati A, Amici A. Galiè M, et al. Among authors: krampera m. Oncogene. 2008 Apr 17;27(18):2542-51. doi: 10.1038/sj.onc.1210920. Epub 2007 Nov 12. Oncogene. 2008. PMID: 17998939
Immune regulation by mesenchymal stem cells derived from adult spleen and thymus.
Krampera M, Sartoris S, Liotta F, Pasini A, Angeli R, Cosmi L, Andreini A, Mosna F, Bonetti B, Rebellato E, Testi MG, Frosali F, Pizzolo G, Tridente G, Maggi E, Romagnani S, Annunziato F. Krampera M, et al. Stem Cells Dev. 2007 Oct;16(5):797-810. doi: 10.1089/scd.2007.0024. Stem Cells Dev. 2007. PMID: 17999601
206 results