Brink R - Search Results

1

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.

Vince JE, Chau D, Callus B, Wong WW, Hawkins CJ, Schneider P, McKinlay M, Benetatos CA, Condon SM, Chunduru SK, Yeoh G, Brink R, Vaux DL, Silke J. Vince JE, et al. Among authors: brink r. J Cell Biol. 2008 Jul 14;182(1):171-84. doi: 10.1083/jcb.200801010. Epub 2008 Jul 7. J Cell Biol. 2008. PMID: 18606850 Free PMC article.

2

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis.

Vince JE, Wong WW, Khan N, Feltham R, Chau D, Ahmed AU, Benetatos CA, Chunduru SK, Condon SM, McKinlay M, Brink R, Leverkus M, Tergaonkar V, Schneider P, Callus BA, Koentgen F, Vaux DL, Silke J. Vince JE, et al. Among authors: brink r. Cell. 2007 Nov 16;131(4):682-93. doi: 10.1016/j.cell.2007.10.037. Cell. 2007. PMID: 18022363 Free article.

3

Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs.

Silke J, Brink R. Silke J, et al. Among authors: brink r. Cell Death Differ. 2010 Jan;17(1):35-45. doi: 10.1038/cdd.2009.114. Cell Death Differ. 2010. PMID: 19680262 Review.

4

In vivo control of B-cell survival and antigen-specific B-cell responses.

Chan TD, Gardam S, Gatto D, Turner VM, Silke J, Brink R. Chan TD, et al. Among authors: brink r. Immunol Rev. 2010 Sep;237(1):90-103. doi: 10.1111/j.1600-065X.2010.00942.x. Immunol Rev. 2010. PMID: 20727031 Review.

5

Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response.

Gardam S, Turner VM, Anderton H, Limaye S, Basten A, Koentgen F, Vaux DL, Silke J, Brink R. Gardam S, et al. Among authors: brink r. Blood. 2011 Apr 14;117(15):4041-51. doi: 10.1182/blood-2010-10-312793. Epub 2011 Feb 7. Blood. 2011. PMID: 21300983 Free article.

6

Tumor necrosis factor receptor 2 (TNFR2) signaling is negatively regulated by a novel, carboxyl-terminal TNFR-associated factor 2 (TRAF2)-binding site.

Grech AP, Gardam S, Chan T, Quinn R, Gonzales R, Basten A, Brink R. Grech AP, et al. Among authors: brink r. J Biol Chem. 2005 Sep 9;280(36):31572-81. doi: 10.1074/jbc.M504849200. Epub 2005 Jul 14. J Biol Chem. 2005. PMID: 16020544 Free article.

7

TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor.

Gardam S, Sierro F, Basten A, Mackay F, Brink R. Gardam S, et al. Among authors: brink r. Immunity. 2008 Mar;28(3):391-401. doi: 10.1016/j.immuni.2008.01.009. Epub 2008 Feb 28. Immunity. 2008. PMID: 18313334 Free article.

8

EBI2 unlocks the door to the Tfh cell nursery.

Brink R. Brink R. Immunol Cell Biol. 2016 Aug;94(7):621-2. doi: 10.1038/icb.2016.52. Epub 2016 Jun 14. Immunol Cell Biol. 2016. PMID: 27297442 No abstract available.

9

TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells.

Grech AP, Amesbury M, Chan T, Gardam S, Basten A, Brink R. Grech AP, et al. Among authors: brink r. Immunity. 2004 Nov;21(5):629-42. doi: 10.1016/j.immuni.2004.09.011. Immunity. 2004. PMID: 15539150 Free article.

10

Targeted deletion of Traf2 allows immunosuppression-free islet allograft survival in mice.

Villanueva JE, Walters SN, Saito M, Malle EK, Zammit NW, Watson KA, Brink R, La Gruta NL, Alexander SI, Grey ST. Villanueva JE, et al. Among authors: brink r. Diabetologia. 2017 Apr;60(4):679-689. doi: 10.1007/s00125-016-4198-7. Epub 2017 Jan 6. Diabetologia. 2017. PMID: 28062921

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