Kovacs A - Search Results

1

Improved retroviral vector design results in sustained expression after adult gene therapy in mucopolysaccharidosis I mice.

Herati RS, Ma X, Tittiger M, Ohlemiller KK, Kovacs A, Ponder KP. Herati RS, et al. Among authors: kovacs a. J Gene Med. 2008 Sep;10(9):972-82. doi: 10.1002/jgm.1229. J Gene Med. 2008. PMID: 18613275 Free PMC article.

2

Upregulation of elastase proteins results in aortic dilatation in mucopolysaccharidosis I mice.

Ma X, Tittiger M, Knutsen RH, Kovacs A, Schaller L, Mecham RP, Ponder KP. Ma X, et al. Among authors: kovacs a. Mol Genet Metab. 2008 Jul;94(3):298-304. doi: 10.1016/j.ymgme.2008.03.018. Epub 2008 May 13. Mol Genet Metab. 2008. PMID: 18479957 Free PMC article.

3

A self-inactivating gamma-retroviral vector reduces manifestations of mucopolysaccharidosis I in mice.

Metcalf JA, Ma X, Linders B, Wu S, Schambach A, Ohlemiller KK, Kovacs A, Bigg M, He L, Tollefsen DM, Ponder KP. Metcalf JA, et al. Among authors: kovacs a. Mol Ther. 2010 Feb;18(2):334-42. doi: 10.1038/mt.2009.236. Epub 2009 Oct 20. Mol Ther. 2010. PMID: 19844196 Free PMC article.

4

Liver-directed neonatal gene therapy prevents cardiac, bone, ear, and eye disease in mucopolysaccharidosis I mice.

Liu Y, Xu L, Hennig AK, Kovacs A, Fu A, Chung S, Lee D, Wang B, Herati RS, Mosinger Ogilvie J, Cai SR, Parker Ponder K. Liu Y, et al. Among authors: kovacs a. Mol Ther. 2005 Jan;11(1):35-47. doi: 10.1016/j.ymthe.2004.08.027. Mol Ther. 2005. PMID: 15585404 Free article.

5

Improvements in mucopolysaccharidosis I mice after adult retroviral vector-mediated gene therapy with immunomodulation.

Ma X, Liu Y, Tittiger M, Hennig A, Kovacs A, Popelka S, Wang B, Herati R, Bigg M, Ponder KP. Ma X, et al. Among authors: kovacs a. Mol Ther. 2007 May;15(5):889-902. doi: 10.1038/sj.mt.6300112. Epub 2007 Feb 20. Mol Ther. 2007. PMID: 17311010 Free article.

6

Repetitive stimulation of autophagy-lysosome machinery by intermittent fasting preconditions the myocardium to ischemia-reperfusion injury.

Godar RJ, Ma X, Liu H, Murphy JT, Weinheimer CJ, Kovacs A, Crosby SD, Saftig P, Diwan A. Godar RJ, et al. Among authors: kovacs a. Autophagy. 2015;11(9):1537-60. doi: 10.1080/15548627.2015.1063768. Autophagy. 2015. PMID: 26103523 Free PMC article.

7

Transcription Factor EB Activation Rescues Advanced αB-Crystallin Mutation-Induced Cardiomyopathy by Normalizing Desmin Localization.

Ma X, Mani K, Liu H, Kovacs A, Murphy JT, Foroughi L, French BA, Weinheimer CJ, Kraja A, Benjamin IJ, Hill JA, Javaheri A, Diwan A. Ma X, et al. Among authors: kovacs a. J Am Heart Assoc. 2019 Feb 19;8(4):e010866. doi: 10.1161/JAHA.118.010866. J Am Heart Assoc. 2019. PMID: 30773991 Free PMC article.

8

TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis.

Ma X, Rawnsley DR, Kovacs A, Islam M, Murphy JT, Zhao C, Kumari M, Foroughi L, Liu H, Qi K, Diwan A, Hyrc K, Evans S, Satoh T, French BA, Margulies KB, Javaheri A, Razani B, Mann DL, Mani K, Diwan A. Ma X, et al. Among authors: kovacs a. JACC Basic Transl Sci. 2021 Dec 17;7(3):223-243. doi: 10.1016/j.jacbts.2021.12.002. eCollection 2022 Mar. JACC Basic Transl Sci. 2021. PMID: 35411325 Free PMC article.

9

Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner.

Russell LK, Mansfield CM, Lehman JJ, Kovacs A, Courtois M, Saffitz JE, Medeiros DM, Valencik ML, McDonald JA, Kelly DP. Russell LK, et al. Among authors: kovacs a. Circ Res. 2004 Mar 5;94(4):525-33. doi: 10.1161/01.RES.0000117088.36577.EB. Epub 2004 Jan 15. Circ Res. 2004. PMID: 14726475

10

Hedgehog signaling is critical for maintenance of the adult coronary vasculature in mice.

Lavine KJ, Kovacs A, Ornitz DM. Lavine KJ, et al. Among authors: kovacs a. J Clin Invest. 2008 Jul;118(7):2404-14. doi: 10.1172/JCI34561. J Clin Invest. 2008. PMID: 18568073 Free PMC article.

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