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Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification.
Maeder ML, Thibodeau-Beganny S, Osiak A, Wright DA, Anthony RM, Eichtinger M, Jiang T, Foley JE, Winfrey RJ, Townsend JA, Unger-Wallace E, Sander JD, Müller-Lerch F, Fu F, Pearlberg J, Göbel C, Dassie JP, Pruett-Miller SM, Porteus MH, Sgroi DC, Iafrate AJ, Dobbs D, McCray PB Jr, Cathomen T, Voytas DF, Joung JK. Maeder ML, et al. Among authors: cathomen t. Mol Cell. 2008 Jul 25;31(2):294-301. doi: 10.1016/j.molcel.2008.06.016. Mol Cell. 2008. PMID: 18657511 Free PMC article.
Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells.
Kath J, Franke C, Drosdek V, Du W, Glaser V, Fuster-Garcia C, Stein M, Zittel T, Schulenberg S, Porter CE, Andersch L, Künkele A, Alcaniz J, Hoffmann J, Abken H, Abou-El-Enein M, Pruß A, Suzuki M, Cathomen T, Stripecke R, Volk HD, Reinke P, Schmueck-Henneresse M, Wagner DL. Kath J, et al. Among authors: cathomen t. bioRxiv [Preprint]. 2023 Nov 14:2023.11.10.565518. doi: 10.1101/2023.11.10.565518. bioRxiv. 2023. Update in: Blood. 2024 Jun 20;143(25):2599-2611. doi: 10.1182/blood.2023020973. PMID: 38116030 Free PMC article. Updated. Preprint.
Clinical genome editing to treat sickle cell disease-A brief update.
Zarghamian P, Klermund J, Cathomen T. Zarghamian P, et al. Among authors: cathomen t. Front Med (Lausanne). 2023 Jan 9;9:1065377. doi: 10.3389/fmed.2022.1065377. eCollection 2022. Front Med (Lausanne). 2023. PMID: 36698803 Free PMC article. Review.
Custom zinc-finger nucleases for use in human cells.
Alwin S, Gere MB, Guhl E, Effertz K, Barbas CF 3rd, Segal DJ, Weitzman MD, Cathomen T. Alwin S, et al. Among authors: cathomen t. Mol Ther. 2005 Oct;12(4):610-7. doi: 10.1016/j.ymthe.2005.06.094. Mol Ther. 2005. PMID: 16039907 Free article.
161 results